Exatecan intermediate 9

Modify Date: 2024-01-30 08:07:21

Exatecan intermediate 9 Structure
Exatecan intermediate 9 structure
Common Name Exatecan intermediate 9
CAS Number 2290562-59-1 Molecular Weight 477.48
Density N/A Boiling Point N/A
Molecular Formula C26H24FN3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Exatecan intermediate 9


Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM)[1].

 Names

Name Exatecan intermediate 9

 Exatecan intermediate 9 Biological Activity

Description Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM)[1].
Related Catalog
References

[1]. Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.  

 Chemical & Physical Properties

Molecular Formula C26H24FN3O5
Molecular Weight 477.48
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