S-acetyl-PEG3-phosphonic acid ethyl ester

Modify Date: 2024-01-15 19:36:51

S-acetyl-PEG3-phosphonic acid ethyl ester Structure
S-acetyl-PEG3-phosphonic acid ethyl ester structure
Common Name S-acetyl-PEG3-phosphonic acid ethyl ester
CAS Number 2173125-29-4 Molecular Weight 372.41
Density N/A Boiling Point N/A
Molecular Formula C14H29O7PS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S-acetyl-PEG3-phosphonic acid ethyl ester


S-acetyl-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name S-acetyl-PEG3-phosphonic acid ethyl ester
Synonym More Synonyms

  Biological Activity

Description S-acetyl-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H29O7PS
Molecular Weight 372.41

 Synonyms

MFCD29042343