Estrogen receptor modulator 8

Modify Date: 2024-01-14 10:04:19

Estrogen receptor modulator 8 structure	Common Name	Estrogen receptor modulator 8
	CAS Number	2170766-56-8	Molecular Weight	460.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₄F₄N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Estrogen receptor modulator 8

Estrogen receptor modulator 8 (compound 4) is an orally active inhibitor of Estrogen Receptor/ERR α (IC50=0.437 nM, MCF-7 cells). Estrogen receptor modulator 8 inhibits MCF-7 cells proliferation with an IC50 value of 0.1 nM[1].

Name	Estrogen receptor modulator 8

Description	Estrogen receptor modulator 8 (compound 4) is an orally active inhibitor of Estrogen Receptor/ERR α (IC50=0.437 nM, MCF-7 cells). Estrogen receptor modulator 8 inhibits MCF-7 cells proliferation with an IC50 value of 0.1 nM[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Endocrinology
Target	IC50: 0.437 nM (ERR α in MCF-7 cells)
References	[1]. Guan D, et al. Preparation of 3-[4-(tetrahydro-1H-pyrrolo[3,4-b]indol-1-yl)phenyl]acrylic acid compound useful as estrogen receptor down-regulator (SERD). World Intellectual Property Organization, WO2018001232 A1. 2018-01-04.

Molecular Formula	C₂₅H₂₄F₄N₂O₂
Molecular Weight	460.46
InChIKey	YEXPBMOTKRZKGQ-XSIBSEMJSA-N
SMILES	CC1Cc2c([nH]c3cccc(F)c23)C(c2c(F)cc(C=CC(=O)O)cc2F)N1CC(C)(C)F

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Estrogen receptor modulator 8

Use of Estrogen receptor modulator 8

Names

Estrogen receptor modulator 8 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.