2170766-56-8

2170766-56-8 structure

Name: Estrogen receptor modulator 8
Chemical Name: Estrogen receptor modulator 8
CAS Number: 2170766-56-8
Molecular Formula: C₂₅H₂₄F₄N₂O₂
Molecular Weight: 460.46
Catalog: Research Areas Endocrinology
Create Date: 2023-09-20 06:43:05
Modify Date: 2024-01-14 10:04:19
Estrogen receptor modulator 8 (compound 4) is an orally active inhibitor of Estrogen Receptor/ERR α (IC50=0.437 nM, MCF-7 cells). Estrogen receptor modulator 8 inhibits MCF-7 cells proliferation with an IC50 value of 0.1 nM[1].

Name	Estrogen receptor modulator 8

Description	Estrogen receptor modulator 8 (compound 4) is an orally active inhibitor of Estrogen Receptor/ERR α (IC50=0.437 nM, MCF-7 cells). Estrogen receptor modulator 8 inhibits MCF-7 cells proliferation with an IC50 value of 0.1 nM[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Endocrinology
Target	IC50: 0.437 nM (ERR α in MCF-7 cells)
References	[1]. Guan D, et al. Preparation of 3-[4-(tetrahydro-1H-pyrrolo[3,4-b]indol-1-yl)phenyl]acrylic acid compound useful as estrogen receptor down-regulator (SERD). World Intellectual Property Organization, WO2018001232 A1. 2018-01-04.

Molecular Formula	C₂₅H₂₄F₄N₂O₂
Molecular Weight	460.46