N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5

Modify Date: 2024-02-28 22:37:45

N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 Structure
N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 structure
Common Name N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5
CAS Number 2107273-42-5 Molecular Weight 840.44
Density N/A Boiling Point N/A
Molecular Formula C44H62ClN5O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5


N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5

 N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 Biological Activity

Description N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C44H62ClN5O9
Molecular Weight 840.44

 Safety Information

Hazard Codes Xi