NH2-PEG2-methyl acetate hydrochloride

Modify Date: 2023-05-31 21:24:31

NH2-PEG2-methyl acetate hydrochloride Structure
NH2-PEG2-methyl acetate hydrochloride structure
Common Name NH2-PEG2-methyl acetate hydrochloride
CAS Number 208647-73-8 Molecular Weight 213.66
Density N/A Boiling Point N/A
Molecular Formula C7H16ClNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH2-PEG2-methyl acetate hydrochloride


NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name NH2-PEG2-methyl acetate hydrochloride

 NH2-PEG2-methyl acetate hydrochloride Biological Activity

Description NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562  

 Chemical & Physical Properties

Molecular Formula C7H16ClNO4
Molecular Weight 213.66
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