208647-73-8

208647-73-8 structure

208647-73-8 structure

Name: NH2-PEG2-methyl acetate hydrochloride
Chemical Name: NH2-PEG2-methyl acetate hydrochloride
CAS Number: 208647-73-8
Molecular Formula: C₇H₁₆ClNO₄
Molecular Weight: 213.66
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2023-05-31 21:24:31
Modify Date: 2023-05-31 21:24:31
NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	NH2-PEG2-methyl acetate hydrochloride

Description	NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> PROTAC >> PROTAC Linker
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₇H₁₆ClNO₄
Molecular Weight	213.66