Chimmitecan

Modify Date: 2024-01-12 18:02:10

Chimmitecan structure	Common Name	Chimmitecan
	CAS Number	185425-25-6	Molecular Weight	404.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₀N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Chimmitecan

Chimmitecan ((S)-9-Allyl-10-Hydroxycamptothecin), a novel 9-small-alkyl-substituted lipophilic Camptothecin (HY-16560), is a potent inhibitor of topoisomerase I. Chimmitecan exhibits anticancer activity[1].

Name	1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione,4-ethyl-4,9-dihydroxy-10-(2-propen-1-yl)-,(4S)
Synonym	More Synonyms

Description	Chimmitecan ((S)-9-Allyl-10-Hydroxycamptothecin), a novel 9-small-alkyl-substituted lipophilic Camptothecin (HY-16560), is a potent inhibitor of topoisomerase I. Chimmitecan exhibits anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
References	[1]. Huang M, et, al. Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo. Clin Cancer Res. 2007 Feb 15;13(4):1298-307.

Molecular Formula	C₂₃H₂₀N₂O₅
Molecular Weight	404.42
Exact Mass	404.13700
PSA	101.65000
LogP	2.51370

(S)-9-Allyl-10-hydroxycamptothecin

UNII-889O97XDAD

Chimmitecan

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Chimmitecan

Use of Chimmitecan

Names

Chimmitecan Biological Activity

Chemical & Physical Properties

Synonyms