NOTA-AE105

Modify Date: 2024-04-13 21:01:29

NOTA-AE105 Structure
NOTA-AE105 structure
Common Name NOTA-AE105
CAS Number 1820563-84-5 Molecular Weight 1511.68
Density N/A Boiling Point N/A
Molecular Formula C72H102N16O20 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NOTA-AE105


NOTA-AE105 is an PET ligand of urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled by 64Cu and 68Ga. 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 shows high image contrast, resulting in clear tumor delineation[1][2].

 Names

Name NOTA-AE105

 NOTA-AE105 Biological Activity

Description NOTA-AE105 is an PET ligand of urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled by 64Cu and 68Ga. 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 shows high image contrast, resulting in clear tumor delineation[1][2].
Related Catalog
Target

Urokinase-type plasminogen activator receptor (uPAR)[2]

References

[1]. Risør LM, et al. Prognostic Value of Urokinase-Type Plasminogen Activator Receptor PET/CT in Head and Neck Squamous Cell Carcinomas and Comparison with 18F-FDG PET/CT: A Single-Center Prospective Study. J Nucl Med. 2022 Aug;63(8):1169-1176.  

[2]. Persson M, et al. uPAR is a promising new imaging biomarker in glioblastoma[J]. Journal of Nuclear Medicine, 2015.

 Chemical & Physical Properties

Molecular Formula C72H102N16O20
Molecular Weight 1511.68
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