1820563-84-5

1820563-84-5 structure

Name: NOTA-AE105
Chemical Name: NOTA-AE105
CAS Number: 1820563-84-5
Molecular Formula: C₇₂H₁₀₂N₁₆O₂₀
Molecular Weight: 1511.68
Catalog: Research Areas Cancer
Create Date: 2023-07-19 21:12:12
Modify Date: 2024-04-13 21:01:29
NOTA-AE105 is an PET ligand of urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled by 64Cu and 68Ga. 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 shows high image contrast, resulting in clear tumor delineation[1][2].

Name	NOTA-AE105

Description	NOTA-AE105 is an PET ligand of urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled by 64Cu and 68Ga. 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 shows high image contrast, resulting in clear tumor delineation[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	Urokinase-type plasminogen activator receptor (uPAR)[2]
References	[1]. Risør LM, et al. Prognostic Value of Urokinase-Type Plasminogen Activator Receptor PET/CT in Head and Neck Squamous Cell Carcinomas and Comparison with 18F-FDG PET/CT: A Single-Center Prospective Study. J Nucl Med. 2022 Aug;63(8):1169-1176. [2]. Persson M, et al. uPAR is a promising new imaging biomarker in glioblastoma[J]. Journal of Nuclear Medicine, 2015.

Molecular Formula	C₇₂H₁₀₂N₁₆O₂₀
Molecular Weight	1511.68