Synstatin (92-119)

Modify Date: 2025-08-27 09:44:55

Synstatin (92-119) Structure
Synstatin (92-119) structure
Common Name Synstatin (92-119)
CAS Number 1259384-47-8 Molecular Weight 3032.27
Density N/A Boiling Point N/A
Molecular Formula C133H207N35O46 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Synstatin (92-119)


Synstatin (92-119) is an anti-tumor agent that inhibits angiogenesis and cancer cell invasion. Synstatin (92-119) down-regulates integrin α?β3 and reduces the activation of angiogenic growth factors VEGF and FGF-2[1][2].

 Names

Name Synstatin (92-119)

 Synstatin (92-119) Biological Activity

Description Synstatin (92-119) is an anti-tumor agent that inhibits angiogenesis and cancer cell invasion. Synstatin (92-119) down-regulates integrin α?β3 and reduces the activation of angiogenic growth factors VEGF and FGF-2[1][2].
Related Catalog
References

[1]. Metwaly HA, et al. Inhibition of the signaling pathway of syndecan-1 by synstatin: A promising anti-integrin inhibitor of angiogenesis and proliferation in HCC in rats. Arch Biochem Biophys. 2018 Aug 15;652:50-58.  

[2]. Rapraeger AC. Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1R-αvβ3 integrin complex in tumorigenesis and angiogenesis. FEBS J. 2013 May;280(10):2207-15.  

 Chemical & Physical Properties

Molecular Formula C133H207N35O46
Molecular Weight 3032.27
InChIKey ZRFCJNAJRWUHMX-CFNXPHSLSA-N
SMILES CC(C)CC(N)C(=O)N1CCCC1C(=O)NC(C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NC(C(=O)NC(CC(C)C)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)O)C(C)O)C(C)C)C(C)C
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