1259384-47-8

1259384-47-8 structure

Name: Synstatin (92-119)
Chemical Name: Synstatin (92-119)
CAS Number: 1259384-47-8
Molecular Formula: C₁₃₃H₂₀₇N₃₅O₄₆
Molecular Weight: 3032.27
Catalog: Signaling Pathways Cytoskeleton Integrin
Create Date: 2023-11-03 13:47:51
Modify Date: 2024-01-04 12:46:38
Synstatin (92-119) is an anti-tumor agent that inhibits angiogenesis and cancer cell invasion. Synstatin (92-119) down-regulates integrin α?β3 and reduces the activation of angiogenic growth factors VEGF and FGF-2[1][2].

Name	Synstatin (92-119)

Description	Synstatin (92-119) is an anti-tumor agent that inhibits angiogenesis and cancer cell invasion. Synstatin (92-119) down-regulates integrin α?β3 and reduces the activation of angiogenic growth factors VEGF and FGF-2[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> Integrin
References	[1]. Metwaly HA, et al. Inhibition of the signaling pathway of syndecan-1 by synstatin: A promising anti-integrin inhibitor of angiogenesis and proliferation in HCC in rats. Arch Biochem Biophys. 2018 Aug 15;652:50-58. [2]. Rapraeger AC. Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1R-αvβ3 integrin complex in tumorigenesis and angiogenesis. FEBS J. 2013 May;280(10):2207-15.

Molecular Formula	C₁₃₃H₂₀₇N₃₅O₄₆
Molecular Weight	3032.27