2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine

Modify Date: 2025-09-10 15:45:04

2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine Structure
2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine structure
Common Name 2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine
CAS Number 109304-11-2 Molecular Weight 315.32
Density N/A Boiling Point N/A
Molecular Formula C11H14FN5O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine


2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine

  Biological Activity

Description 2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C11H14FN5O3S
Molecular Weight 315.32
InChIKey SLPSXWQJKHAIQV-GQTRHBFLSA-N
SMILES CSc1nc(N)nc2c1ncn2C1OC(CO)C(O)C1F
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