2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine

Names

[ CAS No. ]:
109304-11-2

[ Name ]:
2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine

Biological Activity

[Description]:

2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H14FN5O3S

[ Molecular Weight ]:
315.32

Related Compounds