3’-Amino-3’-deoxy-5-methyl uridine

Modify Date: 2024-03-02 11:02:34

3’-Amino-3’-deoxy-5-methyl uridine Structure
3’-Amino-3’-deoxy-5-methyl uridine structure
Common Name 3’-Amino-3’-deoxy-5-methyl uridine
CAS Number 108630-07-5 Molecular Weight 257.24
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H15N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-Amino-3’-deoxy-5-methyl uridine


3’-Amino-3’-deoxy-5-methyl uridine, Anticancer antiviral agent is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,3R,4S,5S)-4-amino-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione

 3’-Amino-3’-deoxy-5-methyl uridine Biological Activity

Description 3’-Amino-3’-deoxy-5-methyl uridine, Anticancer antiviral agent is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C10H15N3O5
Molecular Weight 257.24
Exact Mass 257.101166
LogP -1.29
Index of Refraction 1.597
InChIKey XTMUVONJUKLBOY-JXOAFFINSA-N
SMILES Cc1cn(C2OC(CO)C(N)C2O)c(=O)[nH]c1=O
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