AMG-076

Modify Date: 2024-01-09 05:28:31

AMG-076 structure	Common Name	AMG-076
	CAS Number	1001438-96-5	Molecular Weight	620.72300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₃₉F₃N₂O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AMG-076

AMG-076 is an orally bioavailable and selective MCHR1 antagonist. AMG-076 results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice[1].

Name	1-[2-[(4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]cyclohexane-1-carboxylic acid,benzenesulfonic acid
Synonym	More Synonyms

Description	AMG-076 is an orally bioavailable and selective MCHR1 antagonist. AMG-076 results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> MCHR1 (GPR24) Research Areas >> Metabolic Disease
References	[1]. Alykhan S Motani, et al. Evaluation of AMG 076, a potent and selective MCHR1 antagonist, in rodent and primate obesity models. Pharmacol Res Perspect. 2013 Oct;1(1):e00003.

Molecular Formula	C₃₂H₃₉F₃N₂O₅S
Molecular Weight	620.72300
Exact Mass	620.25300
PSA	119.08000
LogP	8.16160

unii-ogb0t3ag23

amg 076

AMG-076

Use of AMG-076

Names

AMG-076 Biological Activity

Chemical & Physical Properties

Synonyms