693823-79-9
693823-79-9 structure
- Name: AMG-076
- Chemical Name: 1-[2-[(4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]cyclohexane-1-carboxylic acid
- CAS Number: 693823-79-9
- Molecular Formula: C26H33F3N2O2
- Molecular Weight: 462.54800
- Create Date: 2017-06-06 10:21:48
- Modify Date: 2025-08-28 09:36:44
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AMG-076 is a potent, selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1) with binding IC50 of 0.6 nM, with dramatically reduced hERG liability (IC50>5 uM).
| Name | 1-[2-[(4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]cyclohexane-1-carboxylic acid |
|---|---|
| Synonyms |
UNII-HX4T7JEV3D
AMG-076 free base AMG 076 |
| Molecular Formula | C26H33F3N2O2 |
|---|---|
| Molecular Weight | 462.54800 |
| Exact Mass | 462.24900 |
| PSA | 56.33000 |
| LogP | 6.14750 |