Cresyl Violet acetate
Cresyl Violet acetate structure
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Common Name | Cresyl Violet acetate | ||
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| CAS Number | 10510-54-0 | Molecular Weight | 321.330 | |
| Density | N/A | Boiling Point | 468.3ºC | |
| Molecular Formula | C18H15N3O3 | Melting Point | 140-143 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 237ºC | |
Use of Cresyl Violet acetateCresyl violet acetate is a red fluorescent stain, which can be used to stain neurons. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | cresyl violet acetate |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Cresyl violet acetate is a red fluorescent stain, which can be used to stain neurons. |
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| Related Catalog | |
| In Vitro | The estimated total number of SG neurons is 27,485±3251 and 26,705±1823 in the PV and Cresyl violet acetate stained sections, respectively. There is no significant difference between them (p=0.552). Therefore, Cresyl violet acetate staining is simpler and more cost effective when estimates neuronal number. Although PV stains spiral ganglion neurons (SGNs) with a greater intensity and provides a functional status, its tedious protocol limits its use for quantification. Total RC volume is estimated using probe and it is found that an average RC volume of 2.162±0.35 mm3 and 1.82±0.33 mm3 in Cresyl violet acetate staining and PV immunostaining sections, respectively. Volume of neurons is estimated using nucleator probe and it is 3487.63±951 μm3 and 3740.1±784 μm3 in Cresyl violet acetate staining and PV immunostaining sections, respectively. Similarly, volume of neuronal nucleus is also estimated using nucleator probe and it is found to be 131.68±50 μm3 and 126.51±33 μm3 in Cresyl violet acetate staining and PV immunostaining sections, respectively[1]. |
| Cell Assay | Cochlear sections containing SGNs are placed in 24 wells plates containing PBS (pH 7.4) and stored at 4°C. The sections are then used for Cresyl violet acetate and immunohistochemical (IHC) staining. Every 7th section is stained with Cresyl violet acetate (1%), dehydrated with ascending grades of alcohol, cleared with xylene, mounted with DPX and observed under microscope. Approximately 12-13 Cresyl violet acetate staining sections from each specimen are used for stereology. None of these cases show any histopathological changes under the light microscope. Estimation of the total volume of the Rosenthal canal (RC), total number of SGNs (optical fractionator probe) and the volume of the soma and their nucleus (nucleator probe) is done with software[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Boiling Point | 468.3ºC |
|---|---|
| Melting Point | 140-143 °C(lit.) |
| Molecular Formula | C18H15N3O3 |
| Molecular Weight | 321.330 |
| Flash Point | 237ºC |
| Exact Mass | 321.111328 |
| PSA | 113.20000 |
| LogP | 3.91930 |
| Vapour Pressure | 6.07E-09mmHg at 25°C |
| InChIKey | ORIKHDNZZCTIAD-UHFFFAOYSA-N |
| SMILES | CC(=O)O.N=c1ccc2nc3c(cc(N)c4ccccc43)oc-2c1 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S37/39-S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Orthotopic transplantation of immortalized mesencephalic progenitors (CSM14.1 cells) into the substantia nigra of hemiparkinsonian rats induces neuronal differentiation and motoric improvement.
J. Anat. 212(1) , 19-30, (2008) Neural progenitor cell grafting is a promising therapeutic option in the treatment of Parkinson's disease. In previous experiments we grafted temperature-sensitive immortalized CSM14.1 cells, derived ... |
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Analysis and testing of biological stains--the Biological Stain Commission Procedures.
Biotech. Histochem. 77(5&6) , 237-275, (2002)
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The terminal pathway of the complement system is activated in focal penetrating but not in mild diffuse traumatic brain injury.
J. Neurotrauma 30(23) , 1954-65, (2013) The complement system plays an important role in the inflammatory response activated by many central nervous system disorders. However, its significance in traumatic diffuse traumatic axonal injury (T... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
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Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 5H-benzo[a]phenoxazin-9-amine, 5-imino-, acetate (1:1) |
| Cresyl Violet acetate |
| MFCD00013151 |
| CRESYL ECHT VIOLETT |
| Cresyl Violet acetate,certified |
| Cresyl Violet acetate,high purity biological stain |
| Cresyl Violet acetate,certified,pure |
| CRESYL VIOLET |
| CRESYL ECHT VIOLET |
| 5H-Benzo[a]phenoxazin-5-iminium, 9-amino- acetate (1:1) |
| CRESYL VIOLETT |
| Cresyl Violet acetate,pure,certified |
| EINECS 234-043-3 |
| 9-Amino-5H-benzo[a]phenoxazin-5-iminium acetate |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of cresyl violet acetate? |
| A: InChIKey of cresyl violet acetate is ORIKHDNZZCTIAD-UHFFFAOYSA-N. |
| Q: What is the safety information for cresyl violet acetate? |
| A: Safety information for cresyl violet acetate: S37/39-S26. |
| Q: What is the LogP of cresyl violet acetate? |
| A: LogP of cresyl violet acetate is 3.91930. |
| Q: What are the uses of cresyl violet acetate? |
| A: Main uses of cresyl violet acetate: Cresyl violet acetate is a red fluorescent stain, which can be used to stain neurons. |
| Q: What is the melting point of cresyl violet acetate? |
| A: Melting point of cresyl violet acetate is 140-143 °C(lit.). |
| Q: What is the English name of cresyl violet acetate? |
| A: The English name of cresyl violet acetate is cresyl violet acetate. |
| Q: What is the CAS number of cresyl violet acetate? |
| A: CAS number of cresyl violet acetate is 10510-54-0. |
| Q: What English synonyms does cresyl violet acetate have? |
| A: English synonyms of cresyl violet acetate: 5H-benzo[a]phenoxazin-9-amine, 5-imino-, acetate (1:1), Cresyl Violet acetate, MFCD00013151, CRESYL ECHT VIOLETT, Cresyl Violet acetate,certified, Cresyl Violet acetate,high purity biological stain, Cresyl Violet acetate,certified,pure, CRESYL VIOLET, CRESYL ECHT VIOLET, 5H-Benzo[a]phenoxazin-5-iminium, 9-amino- acetate (1:1), CRESYL VIOLETT, Cresyl Violet acetate,pure,certified, EINECS 234-043-3, 9-Amino-5H-benzo[a]phenoxazin-5-iminium acetate. |
| Q: What is the SMILES notation of cresyl violet acetate? |
| A: SMILES notation of cresyl violet acetate is CC(=O)O.N=c1ccc2nc3c(cc(N)c4ccccc43)oc-2c1. |
| Q: What is the polar surface area (PSA) of cresyl violet acetate? |
| A: Polar surface area (PSA) of cresyl violet acetate is 113.20000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |