Syringin

Modify Date: 2026-06-30 04:35:25

Syringin Structure
Syringin structure
Common Name Syringin
CAS Number 118-34-3 Molecular Weight 372.367
Density 1.4±0.1 g/cm3 Boiling Point 642.6±55.0 °C at 760 mmHg
Molecular Formula C17H24O9 Melting Point 192°C
MSDS Chinese USA Flash Point 342.4±31.5 °C

 Use of Syringin


Syringin is a main bioactive phenolic glycoside in Acanthopanax senticosus, with anti-osteoporosis activity. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy[1][2].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name Syringin
Synonym More Synonyms

 Syringin Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Syringin is a main bioactive phenolic glycoside in Acanthopanax senticosus, with anti-osteoporosis activity. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy[1][2].
Related Catalog
References

[1]. Liu J, et al. Syringin prevents bone loss in ovariectomized mice via TRAF6 mediated inhibition of NF-κB and stimulation of PI3K/AKT. Phytomedicine. 2018 Mar 15;42:43-50.

[2]. Li F, et al. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy. Int J Mol Med. 2017 Jan;39(1):199-207.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.4±0.1 g/cm3
Boiling Point 642.6±55.0 °C at 760 mmHg
Melting Point 192°C
Molecular Formula C17H24O9
Molecular Weight 372.367
Flash Point 342.4±31.5 °C
Exact Mass 372.142029
PSA 138.07000
LogP -1.94
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.623
InChIKey QJVXKWHHAMZTBY-GCPOEHJPSA-N
SMILES COc1cc(C=CCO)cc(OC)c1OC1OC(CO)C(O)C(O)C1O
Storage condition 2-8°C

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Safety Phrases 24/25
RIDADR NONH for all modes of transport
HS Code 2932999099

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~97%

Syringin Structure

Syringin

CAS#:118-34-3

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Literature: Daubresse, Nicolas; Francesch, Charlette; Mhamdi, Farida; Rolando, Christian Synthesis, 1998 , # 2 p. 157 - 161

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Syringin Structure

Syringin

CAS#:118-34-3

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Literature: Chemische Berichte, , vol. 62, p. 2279

~%

Syringin Structure

Syringin

CAS#:118-34-3

Learn More
Literature: Synthesis, , # 2 p. 157 - 161

~%

Syringin Structure

Syringin

CAS#:118-34-3

Learn More
Literature: Synthesis, , # 2 p. 157 - 161

~%

Syringin Structure

Syringin

CAS#:118-34-3

Learn More
Literature: Synthesis, , # 2 p. 157 - 161

~%

Syringin Structure

Syringin

CAS#:118-34-3

Learn More
Literature: Synthesis, , # 2 p. 157 - 161

~%

Syringin Structure

Syringin

CAS#:118-34-3

Learn More
Literature: Phytochemistry, , vol. 57, # 7 p. 1085 - 1093

~%

Syringin Structure

Syringin

CAS#:118-34-3

Learn More
Literature: Chemische Berichte, , vol. 62, p. 2279

~%

Syringin Structure

Syringin

CAS#:118-34-3

Learn More
Literature: Chemische Berichte, , vol. 88, p. 16,20

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  5

DownStream  0

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles27

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

[Simultaneous determination of five glycosides in Aidi injection by RP-HPLC-ELSD].

Zhongguo Zhong Yao Za Zhi 36(6) , 706-8, (2011)

To develop a RP-HPLC-ELSD method for the simultaneous determination of five glycosides in Aidi injection.The separation was carried out at 35 degrees C on a Kromasil C18 column (4.6 mm x 250 mm, 5 mic...

Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons.

J. Nat. Med. 65(3-4) , 417-23, (2011)

Not only neuronal death but also neuritic atrophy and synaptic loss underlie the pathogenesis of Alzheimer's disease as direct causes of the memory deficit. Extracts of Siberian ginseng (the rhizome o...

[Chemical constituents from Exochorda racemosa].

Zhongguo Zhong Yao Za Zhi 36(9) , 1198-201, (2011)

To study the chemical constituents of Exochorda racemosa.Compounds were isolated and purified by silica gel, Sephadex LH-20, MCI gel and RP-18 column chromatography, and their structures were determin...

 SyringinBioassay

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This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Antiviral activity against HIV1 infected in human 293T cells expressing VSV-G assesse...
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL3094943
Name: Cytotoxicity against human HCT8 cells at 10 uM after 96 hrs by MTT assay
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3094944
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

β-D-Glucopyranoside, 4-(3-hydroxy-1-propenyl)-2,6-dimethoxyphenyl
Sinapyl 4-O-β-D-glucopyranoside alcohol
4-[(1E)-3-Hydroxy-1-propen-1-yl]-2,6-dimethoxyphenyl β-D-glucopyranoside
4-[(1E)-3-Hydroxyprop-1-en-1-yl]-2,6-dimethoxyphenyl β-D-glucopyranoside
MFCD00016778
Eleutheroside B
Ligustrin
Syringin
LILACIN
4-[(1E)-3-Hydroxyprop-1-en-1-yl]-2,6-dimethoxyphenyl-β-D-glucopyranoside
Sinapyl alcohol 4-O-glucoside
β-D-Glucopyranoside, 4-[(1E)-3-hydroxy-1-propenyl]-2,6-dimethoxyphenyl
4-(3-Hydroxypropenyl)-2,6-dimethoxyphenyl-D-glucoside
Methoxyconiferine
β-D-Glucopyranoside, 4-[(1E)-3-hydroxy-1-propen-1-yl]-2,6-dimethoxyphenyl

 Syringin | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of Syringin?
A: The English name of Syringin is Syringin.
Q: What is the LogP of Syringin?
A: LogP of Syringin is -1.94.
Q: What is the molecular formula of Syringin?
A: Molecular formula of Syringin is C17H24O9.
Q: What is the polar surface area (PSA) of Syringin?
A: Polar surface area (PSA) of Syringin is 138.07000.
Q: What is the boiling point of Syringin?
A: Boiling point of Syringin is 642.6±55.0 °C at 760 mmHg.
Q: What is the safety information for Syringin?
A: Safety information for Syringin: 24/25.
Q: What is the molecular weight of Syringin?
A: Molecular weight of Syringin is 372.367.
Q: What are the storage conditions for Syringin?
A: Storage conditions for Syringin: 2-8°C.
Q: What are the uses of Syringin?
A: Main uses of Syringin: Syringin is a main bioactive phenolic glycoside in Acanthopanax senticosus, with anti-osteoporosis activity. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy[1][2].
Q: What are the upstream materials of Syringin?
A: Related upstream materials(CAS) of Syringin: 203179-64-0;572-09-8;83-87-4;134-96-3;4206-58-0.

 Syringinfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
BioBioPha
naturewill
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