PTIO
PTIO structure
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Common Name | PTIO | ||
|---|---|---|---|---|
| CAS Number | 18390-00-6 | Molecular Weight | 233.286 | |
| Density | 1.17g/cm3 | Boiling Point | 359.7ºC at 760mmHg | |
| Molecular Formula | C13H17N2O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 171.3ºC | |
Use of PTIOPTIO is a specific scavenger of NO. PTIO reacts with •NO to form the corresponding imino nitroxides and •NO2[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | ptio |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | PTIO is a specific scavenger of NO. PTIO reacts with •NO to form the corresponding imino nitroxides and •NO2[1]. |
|---|---|
| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.17g/cm3 |
|---|---|
| Boiling Point | 359.7ºC at 760mmHg |
| Molecular Formula | C13H17N2O2 |
| Molecular Weight | 233.286 |
| Flash Point | 171.3ºC |
| Exact Mass | 233.128998 |
| PSA | 31.99000 |
| LogP | 2.05850 |
| InChIKey | DYUUGILMVYJEHY-UHFFFAOYSA-N |
| SMILES | CC1(C)N([O])C(c2ccccc2)=[N+]([O-])C1(C)C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 6 | |
|---|---|
| DownStream 4 | |
CAS#:18389-99-6
CAS#:351902-03-9
CAS#:3964-18-9
CAS#:66166-73-2
CAS#:14384-45-3
CAS#:20485-44-3
CAS#:26731-64-6
CAS#:18390-03-9
CAS#:61919-29-7This table lists relevant public references with title, journal and publication metadata for this compound.
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Nitric oxide induces cancer stem cell-like phenotypes in human lung cancer cells.
Am. J. Physiol. Cell Physiol. 308(2) , C89-100, (2015) Even though tremendous advances have been made in the treatment of cancers during the past decades, the success rate among patients with cancer is still dismal, largely because of problems associated ... |
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Interaction of nNOS with PSD-95 negatively controls regenerative repair after stroke.
J. Neurosci. 34(40) , 13535-48, (2014) Stroke is a major public health concern. The lack of effective therapies heightens the need for new therapeutic targets. Mammalian brain has the ability to rewire itself to restore lost functionalitie... |
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Cardiac contractility in Antarctic teleost is modulated by nitrite through xanthine oxidase and cytochrome p-450 nitrite reductase.
Nitric Oxide 49 , 1-7, (2015) In mammalian and non-mammalian vertebrates, nitrite anion, the largest pool of intravascular and tissue nitric oxide storage, represents a key player of many biological processes, including cardiac mo... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Antioxidant activity assessed as nitric oxide scavenging activity after 60 min by Gri...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1054040
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Name: Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins
Source: ChEMBL
Target: N/A
External Id: CHEMBL1054041
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Name: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL1054039
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Name: Nitric oxide radical scavenging activity in PC12 cells by survival assay
Source: ChEMBL
Target: PC-12
External Id: CHEMBL892548
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Name: Hydrogen peroxide radical scavenging activity in PC12 cell by survival assay
Source: ChEMBL
Target: PC-12
External Id: CHEMBL892549
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Name: Hydroxyl radical scavenging activity in PC12 cell by survival assay
Source: ChEMBL
Target: PC-12
External Id: CHEMBL892550
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Name: Partition coefficient, log P of the compound
Source: ChEMBL
Target: N/A
External Id: CHEMBL892551
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide |
| 2-phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole-3-oxide-1-oxyl |
| 2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL |
| 4,5-Dihydro-4,4,5,5-tetramethyl-3-oxido-2-phenyl-1H-Imidazol-1-yloxy |
| 2-phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazolyl-1-oxy 3-oxide radical |
| 2-phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazolyl-1-oxyl-3-N-oxide |
| 2-phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-oxyl 3-oxide |
| 4,5-DIHYDRO-4,4,5,5-TETRAMETHYL-2-PHENYL-1H-IMIDAZOL-1-YLOXY-1-OXIDE |
| PTIO |
| 2-Phenyl-4,4,5,5-tetramethylimidazoline 3-oxide 1-oxyl |
| 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide |
| 4,4,5,5-tetramethyl-2-phenyl-4,5-dihydro-1H-imidazole-1-oxyl 3-oxide |
| (4,4,5,5-Tetramethyl-3-oxido-2-phenyl-4,5-dihydro-1H-imidazol-1-yl)oxidanyl |
| 2-phenyl-4,4,5,5-tetramethyl-2,5-dihydro-1H-imidazol-1-oxyl 3-N-oxide |
| (2-Phenyl-4,4,5,5-tetraMethyliMidazoline-3-oxide-1-oxyl) |
| 4,4,5,5-tetramethyl-2-phenyl-4,5-dihydro-1H-imidazole-3-oxide-1-oxyl |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the upstream materials of ptio? |
| A: Related upstream materials(CAS) of ptio: 18389-99-6;351902-03-9;3964-18-9;66166-73-2;14384-45-3;20485-44-3. |
| Q: What are the uses of ptio? |
| A: Main uses of ptio: PTIO is a specific scavenger of NO. PTIO reacts with •NO to form the corresponding imino nitroxides and •NO2[1]. |
| Q: What is the LogP of ptio? |
| A: LogP of ptio is 2.05850. |
| Q: What is the SMILES notation of ptio? |
| A: SMILES notation of ptio is CC1(C)N([O])C(c2ccccc2)=[N+]([O-])C1(C)C. |
| Q: What is the CAS number of ptio? |
| A: CAS number of ptio is 18390-00-6. |
| Q: What is the InChIKey of ptio? |
| A: InChIKey of ptio is DYUUGILMVYJEHY-UHFFFAOYSA-N. |
| Q: What is the boiling point of ptio? |
| A: Boiling point of ptio is 359.7ºC at 760mmHg. |
| Q: What is the English name of ptio? |
| A: The English name of ptio is ptio. |
| Q: What is the molecular formula of ptio? |
| A: Molecular formula of ptio is C13H17N2O2. |
| Q: What is the polar surface area (PSA) of ptio? |
| A: Polar surface area (PSA) of ptio is 31.99000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |