4-methylumbelliferyl α-D-galactoside
4-methylumbelliferyl α-D-galactoside structure
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Common Name | 4-methylumbelliferyl α-D-galactoside | ||
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| CAS Number | 38597-12-5 | Molecular Weight | 338.309 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 626.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C16H18O8 | Melting Point | 171-173ºC | |
| MSDS | USA | Flash Point | 233.9±25.0 °C | |
Use of 4-methylumbelliferyl α-D-galactoside4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA[1]. |
Summary: 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate (CAS number: 38597-12-5), molecular formula C16H18O8, molecular weight 338.309, appears as white to off-white crystalline powder, melting point 171-173°C. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA[1]. |
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| Related Catalog | |
| In Vitro | 4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal) has an emission wavelength of 440 nm and an excitation wavelength of 365 nm[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 626.9±55.0 °C at 760 mmHg |
| Melting Point | 171-173ºC |
| Molecular Formula | C16H18O8 |
| Molecular Weight | 338.309 |
| Flash Point | 233.9±25.0 °C |
| Exact Mass | 338.100159 |
| PSA | 129.59000 |
| LogP | -0.46 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.641 |
| InChIKey | YUDPTGPSBJVHCN-CHUNWDLHSA-N |
| SMILES | Cc1cc(=O)oc2cc(OC3OC(CO)C(O)C(O)C3O)ccc12 |
| Storage condition | 2-8°C |
| Water Solubility | H2O: 10 mg/mL hot, clear, colorless |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | T+ |
| Risk Phrases | R26/27/28 |
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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4-methylumbelli... CAS#:38597-12-5 |
| Literature: Constantzas; Kocourek Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 1099,1102 |
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4-methylumbelli... CAS#:38597-12-5 |
| Literature: Constantzas; Kocourek Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 1099,1102 |
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~%
4-methylumbelli... CAS#:38597-12-5 |
| Literature: Constantzas; Kocourek Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 1099,1102 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 3 | |
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| DownStream 2 | |
CAS#:10257-28-0This table lists relevant public references with title, journal and publication metadata for this compound.
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A 45-kDa midgut glycoprotein from Anopheles albimanus mosquito mediates the killing of trypanosomes.
Cell Biochem. Funct. 20(3) , 257-62, (2002) Trypanosomes do not inhabit or grow in anopheles mosquitoes, the vector for the transmission of Plasmodium parasites the causative agent for malaria. The possession of lytic factors by the anopheline ... |
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[A combined chromogenic-fluorogenic medium for the simultaneous detection of coliform groups and E. coli in water].
Zentralbl. Hyg. Umweltmed. 189 , 225, (1989) A comparison was made with different chromogenic and fluorogenic substrates, 4-methylumbelliferyl-beta-D-glucuronide (MUG), 4-nitrophenyl-beta-D-glucuronide (PNPG), 4-methylumbelliferyl-beta-D-galacto... |
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The chaperone activity and toxicity of ambroxol on Gaucher cells and normal mice.
Brain Dev. 35(4) , 317-22, (2013) Gaucher disease (GD), caused by a defect of acid β-glucosidase (β-Glu), is one of the most common sphingolipidoses. Recently, ambroxol, an FDA-approved drug used to treat airway mucus hypersecretion a... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-Methyl-2-oxo-2H-chromen-7-yl α-D-galactopyranoside |
| 4-methylumbelliferyl α-D-galactoside |
| 4-METHYLUMBELLIFERYL-α-D-GALACTOPYRANOSIDE |
| MFCD00063278 |
| EINECS 254-031-1 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: Main uses of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate: 4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA[1]. |
| Q: What is the boiling point of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: Boiling point of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate is 626.9±55.0 °C at 760 mmHg. |
| Q: What are the storage conditions for 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: Storage conditions for 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate: 2-8°C. |
| Q: How is the water solubility of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: Water solubility of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate: H2O: 10 mg/mL hot, clear, colorless. |
| Q: What is the SMILES notation of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: SMILES notation of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate is Cc1cc(=O)oc2cc(OC3OC(CO)C(O)C(O)C3O)ccc12. |
| Q: What is the InChIKey of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: InChIKey of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate is YUDPTGPSBJVHCN-CHUNWDLHSA-N. |
| Q: What is the polar surface area (PSA) of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: Polar surface area (PSA) of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate is 129.59000. |
| Q: What is the LogP of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: LogP of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate is -0.46. |
| Q: What is the CAS number of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: CAS number of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate is 38597-12-5. |
| Q: What is the molecular formula of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate? |
| A: Molecular formula of 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate is C16H18O8. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |