Glutaurine
Glutaurine structure
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Common Name | Glutaurine | ||
|---|---|---|---|---|
| CAS Number | 56488-60-9 | Molecular Weight | 254.26 | |
| Density | 1.52g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C7H14N2O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GlutaurineGlutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia[1][2][3][4]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia[1][2][3][4]. |
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| Related Catalog | |
| In Vivo | Glutaurine (1, 10, 20 or 50 μg/rat; p.o.) significantly restores the latency of entry in both the 24 and 48 hours tests at the dose of 50 μg/rat[2]. Glutaurine (100~3000 ug/kg; i.p.) significantly reduces T3 blood levels in a dose-dependent manner, but does not significantly raise T4 blood levels[3]. Animal Model: CFY male rats (170~250g)[2] Dosage: 1, 10, 20 or 50 μg/rat Administration: P.o. Result: Significantly restored the latency of entry in both the 24 and 48 h tests at the dose of 50 μg/rat. Animal Model: Fischer 344 rats[3] Dosage: 100~3000 ug/kg Administration: I.p. Result: Significantly reduced T3 blood levels in a dose-dependent manner, but did not significantly raise T4 blood levels. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.52g/cm3 |
|---|---|
| Molecular Formula | C7H14N2O6S |
| Molecular Weight | 254.26 |
| Exact Mass | 254.05700 |
| PSA | 155.17000 |
| LogP | 0.35450 |
| Index of Refraction | 1.556 |
| InChIKey | WGXUDTHMEITUBO-YFKPBYRVSA-N |
| SMILES | NC(CCC(=O)NCCS(=O)(=O)O)C(=O)O |
| Storage condition | 2-8°C |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
|
~89%
Glutaurine CAS#:56488-60-9 |
| Literature: Higashiura; Ienaga Synthesis, 1992 , # 4 p. 353 - 354 |
|
~35%
Glutaurine CAS#:56488-60-9 |
| Literature: Tomita, Kenji; Yano, Toshihiro; Zhu, Jixi; Kumagai, Hidehiko; Tochikura, Tatsurokuro Agricultural and Biological Chemistry, 1989 , vol. 53, # 12 p. 3239 - 3244 |
|
~%
Glutaurine CAS#:56488-60-9 |
| Literature: Higashiura, Kunihiko; Ienaga, Kazuharu Journal of Chemical Research, Miniprint, 1992 , p. 1901 - 1921 |
|
~%
Glutaurine CAS#:56488-60-9 |
| Literature: Ienaga; Nakamura; Higashiura; Toyomaki; Kimura Chemical and pharmaceutical bulletin, 1988 , vol. 36, # 8 p. 2796 - 2801 |
|
~%
Glutaurine CAS#:56488-60-9 |
| Literature: Ienaga; Nakamura; Higashiura; Toyomaki; Kimura Chemical and pharmaceutical bulletin, 1988 , vol. 36, # 8 p. 2796 - 2801 |
|
~25%
Glutaurine CAS#:56488-60-9 |
| Literature: Nakayama, Reiko; Kumagai, Hedehiko; Maruyama, Takashi; Tochikura, Tatsurokuro; Ueno, Tamio; Fukami, Hiroshi Agricultural and Biological Chemistry, 1981 , vol. 45, # l2 p. 2839 - 2846 |
|
~%
Glutaurine CAS#:56488-60-9 |
| Literature: Ienaga; Nakamura; Higashiura; Toyomaki; Kimura Chemical and pharmaceutical bulletin, 1988 , vol. 36, # 8 p. 2796 - 2801 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 7 | |
|---|---|
| DownStream 0 | |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Glutaurine |
| Litoralon |
| Glutaurin |
| g-l-glutamyltaurine |
| 5-L-Glutamyl-taurine |
| 5-Glutamyl-taurine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: InChIKey of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid is WGXUDTHMEITUBO-YFKPBYRVSA-N. |
| Q: What is the molecular weight of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: Molecular weight of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid is 254.26. |
| Q: What are the storage conditions for (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: Storage conditions for (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid: 2-8°C. |
| Q: What is the molecular formula of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: Molecular formula of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid is C7H14N2O6S. |
| Q: What is the SMILES notation of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: SMILES notation of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid is NC(CCC(=O)NCCS(=O)(=O)O)C(=O)O. |
| Q: What are the uses of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: Main uses of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid: Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia[1][2][3][4]. |
| Q: What is the LogP of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: LogP of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid is 0.35450. |
| Q: What are the upstream materials of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: Related upstream materials(CAS) of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid: 58238-09-8;56-85-9;107-35-7;30924-93-7;3705-42-8;142-47-2;4821-79-8. |
| Q: What is the polar surface area (PSA) of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: Polar surface area (PSA) of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid is 155.17000. |
| Q: What is the English name of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid? |
| A: The English name of (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid is (2S)-2-amino-5-oxo-5-(2-sulfoethylamino)pentanoic acid. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |