2-indol-3-yl-4-oxo-4-phenylbutanoic acid
Modify Date: 2026-07-01 09:28:36
2-indol-3-yl-4-oxo-4-phenylbutanoic acid structure
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Common Name | 2-indol-3-yl-4-oxo-4-phenylbutanoic acid | ||
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| CAS Number | 6266-66-6 | Molecular Weight | 293.31700 | |
| Density | 1.318 g/cm3 | Boiling Point | 569ºC at 760 mmHg | |
| Molecular Formula | C18H15NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 297.9ºC | |
Use of 2-indol-3-yl-4-oxo-4-phenylbutanoic acidPEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs). |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs). |
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| Related Catalog | |
| In Vitro | PEO-IAA is also an α-alkyl-IAA, and shows more potent anti-auxin activity in auxin-responsive gene expression and in the cell division and elongation pathway that is mediated via SCFTIR1/AFBs. PEO-IAA suppresses not only the expression of an auxin-responsive ZmSAUR2 gene, but also gravitropic curvature. PEO-IAA blocks the auxin response in Arabidopsis, rice, moss and maize[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.318 g/cm3 |
|---|---|
| Boiling Point | 569ºC at 760 mmHg |
| Molecular Formula | C18H15NO3 |
| Molecular Weight | 293.31700 |
| Flash Point | 297.9ºC |
| Exact Mass | 293.10500 |
| PSA | 70.16000 |
| LogP | 3.60910 |
| InChIKey | SJVMWLJNHPHNPT-UHFFFAOYSA-N |
| SMILES | O=C(CC(C(=O)O)c1c[nH]c2ccccc12)c1ccccc1 |
| Storage condition | 2-8℃ |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Validation...
Source: NMMLSC
Target: ATP-binding cassette sub-family B member 6, mitochondrial [Homo sapiens]
External Id: UNMCMD_ABCB6_1o_ValidationSet
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-(1H-indol-3-yl)-4-oxo-4-phenylbutanoic acid |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the SMILES notation of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: SMILES notation of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid is O=C(CC(C(=O)O)c1c[nH]c2ccccc12)c1ccccc1. |
| Q: What is the English name of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: The English name of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid is 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid. |
| Q: What are the storage conditions for 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: Storage conditions for 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid: 2-8℃. |
| Q: What is the InChIKey of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: InChIKey of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid is SJVMWLJNHPHNPT-UHFFFAOYSA-N. |
| Q: What is the molecular weight of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: Molecular weight of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid is 293.31700. |
| Q: What is the LogP of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: LogP of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid is 3.60910. |
| Q: What are the uses of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: Main uses of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid: PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs). |
| Q: What is the CAS number of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: CAS number of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid is 6266-66-6. |
| Q: What is the molecular formula of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: Molecular formula of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid is C18H15NO3. |
| Q: What is the polar surface area (PSA) of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid? |
| A: Polar surface area (PSA) of 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid is 70.16000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |