2,4-Dichloro-6-methoxyquinoline

Modify Date: 2025-10-24 22:59:09

2,4-Dichloro-6-methoxyquinoline Structure
2,4-Dichloro-6-methoxyquinoline structure
Common Name 2,4-Dichloro-6-methoxyquinoline
CAS Number 70049-46-6 Molecular Weight 228.07500
Density N/A Boiling Point N/A
Molecular Formula C10H7Cl2NO Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 2,4-Dichloro-6-methoxyquinoline
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C10H7Cl2NO
Molecular Weight 228.07500
Exact Mass 226.99000
PSA 22.12000
LogP 3.55020
InChIKey FUAYQQYYACASFP-UHFFFAOYSA-N
SMILES COc1ccc2nc(Cl)cc(Cl)c2c1
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
HS Code 2933499090

 Synthetic Route

~69%

2,4-Dichloro-6-methoxyquinoline Structure

2,4-Dichloro-6-...

CAS#:70049-46-6

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Literature: Arul Prakash; Rajendran Heterocyclic Communications, 2001 , vol. 7, # 4 p. 353 - 358

~18%

2,4-Dichloro-6-methoxyquinoline Structure

2,4-Dichloro-6-...

CAS#:70049-46-6

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Literature: N30 PHARMACEUTICALS, LLC; SUN, Xicheng; QIU, Jian; STOUT, Adam Patent: WO2012/48181 A1, 2012 ; Location in patent: Page/Page column 78 ; WO 2012/048181 A1

~72%

2,4-Dichloro-6-methoxyquinoline Structure

2,4-Dichloro-6-...

CAS#:70049-46-6

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Literature: Ashok; Sridevi; Umadevi Synthesis, 1993 , # 6 p. 623 - 626

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 2,4-Dichloro-6-methoxyquinolineBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Luminescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of ADP-glo R...
Source: Broad Institute
Target: N/A
External Id: 2046-03_INHIBITORS_DOSE-TITRATION_MLPCN-CHERRYPICK
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Luminescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of Glycogen Syn...
Source: Broad Institute
Target: glycogen synthase kinase 3 beta isoform 1 [Homo sapiens]
External Id: 2046-02_INHIBITORS_DOSE-TITRATION_MLPCN-CHERRYPICK
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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 Synonyms

2,4-dichloro-6-methoxyquinoline
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