oxacillin sodium monohydrate
oxacillin sodium monohydrate structure
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Common Name | oxacillin sodium monohydrate | ||
|---|---|---|---|---|
| CAS Number | 7240-38-2 | Molecular Weight | 441.43 | |
| Density | N/A | Boiling Point | 686.8ºC at 760 mmHg | |
| Molecular Formula | C19H20N3NaO6S | Melting Point | 188ºC | |
| MSDS | Chinese USA | Flash Point | 369.2ºC | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
Use of oxacillin sodium monohydrateOxacillin sodium monohydrate is an antibiotic similar to flucloxacillin used in resistant staphylococci infections.Target: AntibacterialOxacillin is a penicillinase-resistant β-lactam. It is similar to methicillin, and has replaced methicillin in clinical use. Another related compound is nafcillin. Since it is resistant to penicillinase enzymes, such as that produced by Staphylococcus aureus, it is widely used clinically in the US to treat penicillin-resistant Staphylococcus aureus. However, with the introduction and widespread use of both oxacillin and methicillin, antibiotic-resistant strains called oxacillin-resistant Staphylococcus aureus (MRSA/ORSA) have become increasingly prevalent worldwide. MRSA/ORSA is treated using vancomycin. From Wikipedia. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | oxacillin sodium monohydrate |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Oxacillin sodium monohydrate is an antibiotic similar to flucloxacillin used in resistant staphylococci infections.Target: AntibacterialOxacillin is a penicillinase-resistant β-lactam. It is similar to methicillin, and has replaced methicillin in clinical use. Another related compound is nafcillin. Since it is resistant to penicillinase enzymes, such as that produced by Staphylococcus aureus, it is widely used clinically in the US to treat penicillin-resistant Staphylococcus aureus. However, with the introduction and widespread use of both oxacillin and methicillin, antibiotic-resistant strains called oxacillin-resistant Staphylococcus aureus (MRSA/ORSA) have become increasingly prevalent worldwide. MRSA/ORSA is treated using vancomycin. From Wikipedia. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Boiling Point | 686.8ºC at 760 mmHg |
|---|---|
| Melting Point | 188ºC |
| Molecular Formula | C19H20N3NaO6S |
| Molecular Weight | 441.43 |
| Flash Point | 369.2ºC |
| PSA | 136.54000 |
| LogP | 0.99210 |
| Index of Refraction | 205 ° (C=1, H2O) |
| InChIKey | SNNRZFMTISMWEY-VICXVTCVSA-N |
| SMILES | Cc1onc(-c2ccccc2)c1C(=O)NC1C(=O)N2C1SC(C)(C)C2C(=O)O.O.[Na] |
| Storage condition | Refrigerator |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H315-H317-H319-H334-H335 |
| Precautionary Statements | P261-P280-P284-P304 + P340-P305 + P351 + P338-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R36/37/38;R42/43 |
| Safety Phrases | S22-S26-S36/37 |
| RIDADR | NONH for all modes of transport |
| HS Code | 3004101900 |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 3004101900 |
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This table lists relevant public references with title, journal and publication metadata for this compound.
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Antimicrobial/anti-biofilm activity of expired blood platelets and their released products.
Postepy. Hig. Med. Dosw. 67 , 321-5, (2013) Although platelets are not part of the classical immune system, they have many features that indicate their role in the anti-infective host defense. They come into interactions with microorganisms, wh... |
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Antimicrobial susceptibility of animal and human isolates of Clostridium difficile by broth microdilution.
J. Med. Microbiol. 62(Pt 9) , 1478-85, (2013) A total of 188 human (n = 92) and animal (n = 96) isolates of Clostridium difficile of different PCR ribotypes were screened for susceptibility to 30 antimicrobials using broth microdilution. When com... |
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Antibacterial Characterization of Novel Synthetic Thiazole Compounds against Methicillin-Resistant Staphylococcus pseudintermedius.
PLoS ONE 10 , e0130385, (2015) Staphylococcus pseudintermedius is a commensal organism of companion animals that is a significant source of opportunistic infections in dogs. With the emergence of clinical isolates of S. pseudinterm... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00056864 |
| sodium,(2S,5R,6R)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrate |
| Sodium (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate (1:1:1) |
| Monosodium (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-4-isoxazolecarboxamido)-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate monohydrate |
| Oxacillin Sodium Salt Monohydrate |
| 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]amino]-7-oxo-, sodium salt, (2S,5R,6R)-, hydrate (1:1:1) |
| EINECS 214-636-3 |
| oxacillin sodium |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the SMILES notation of oxacillin sodium monohydrate? |
| A: SMILES notation of oxacillin sodium monohydrate is Cc1onc(-c2ccccc2)c1C(=O)NC1C(=O)N2C1SC(C)(C)C2C(=O)O.O.[Na]. |
| Q: What is the boiling point of oxacillin sodium monohydrate? |
| A: Boiling point of oxacillin sodium monohydrate is 686.8ºC at 760 mmHg. |
| Q: What is the CAS number of oxacillin sodium monohydrate? |
| A: CAS number of oxacillin sodium monohydrate is 7240-38-2. |
| Q: What are the storage conditions for oxacillin sodium monohydrate? |
| A: Storage conditions for oxacillin sodium monohydrate: Refrigerator. |
| Q: What is the InChIKey of oxacillin sodium monohydrate? |
| A: InChIKey of oxacillin sodium monohydrate is SNNRZFMTISMWEY-VICXVTCVSA-N. |
| Q: What is the molecular weight of oxacillin sodium monohydrate? |
| A: Molecular weight of oxacillin sodium monohydrate is 441.43. |
| Q: What is the English name of oxacillin sodium monohydrate? |
| A: The English name of oxacillin sodium monohydrate is oxacillin sodium monohydrate. |
| Q: What is the molecular formula of oxacillin sodium monohydrate? |
| A: Molecular formula of oxacillin sodium monohydrate is C19H20N3NaO6S. |
| Q: What is the polar surface area (PSA) of oxacillin sodium monohydrate? |
| A: Polar surface area (PSA) of oxacillin sodium monohydrate is 136.54000. |
| Q: What is the safety information for oxacillin sodium monohydrate? |
| A: Safety information for oxacillin sodium monohydrate: S22-S26-S36/37. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |