Dextran

Modify Date: 2026-06-30 14:25:47

Dextran Structure
Dextran structure
Common Name Dextran
CAS Number 9004-54-0 Molecular Weight 504.437
Density 1.8±0.1 g/cm3 Boiling Point 952.8±65.0 °C at 760 mmHg
Molecular Formula C18H32O16 Melting Point -114.22ºC
MSDS Chinese USA Flash Point 327.7±27.8 °C
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning

 Use of Dextran


Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose
Synonym More Synonyms

 Dextran Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.
Related Catalog
References

[1]. Bark BP, et al. Infusion rate and plasma volume expansion of dextran and albumin in the septic guinea pig. Acta Anaesthesiol Scand. 2014 Jan;58(1):44-51.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.8±0.1 g/cm3
Boiling Point 952.8±65.0 °C at 760 mmHg
Melting Point -114.22ºC
Molecular Formula C18H32O16
Molecular Weight 504.437
Flash Point 327.7±27.8 °C
Exact Mass 504.169037
PSA 276.52000
LogP -4.26
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.652
InChIKey FZWBNHMXJMCXLU-UHFFFAOYSA-N
SMILES O=CC(O)C(O)C(O)C(O)COC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HH9247500
CHEMICAL NAME :
Dextran 70
CAS REGISTRY NUMBER :
9004-54-0
LAST UPDATED :
199701

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
6 mg/kg
TOXIC EFFECTS :
Cardiac - other changes Vascular - other changes Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 2,1502,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1023,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1023,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1023,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>12 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1023,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1023,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1023,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
17400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1023,1972 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
900 mL/kg/30D-C
TOXIC EFFECTS :
Liver - changes in liver weight Endocrine - changes in adrenal weight Blood - normocytic anemia
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1089,1972
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
4680 mL/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - normocytic anemia Related to Chronic Data - death
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1103,1972
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3120 mL/kg/26W-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - normocytic anemia Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 3,369,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3120 mL/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - normocytic anemia Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 3,369,1975 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
675 gm/kg
SEX/DURATION :
female 8-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1119,1972
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
3640 gm/kg
SEX/DURATION :
male 91 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 3,369,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83342 No. of Facilities: 86 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 369 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83342 No. of Facilities: 432 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 7612 (estimated) No. of Female Employees: 4671 (estimated)

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning
Hazard Statements H373-H411
Precautionary Statements P273
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn,Xi
Risk Phrases R20/21/22
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS HH9230000
HS Code 2932999099

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

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Dextran Structure

Dextran

CAS#:9004-54-0

Learn More
Literature: Carbohydrate Research, , vol. 346, # 9 p. 1077 - 1082

~%

Dextran Structure

Dextran

CAS#:9004-54-0

Learn More
Literature: Journal of Agricultural and Food Chemistry, , vol. 59, # 8 p. 4148 - 4155

~%

Dextran Structure

Dextran

CAS#:9004-54-0

Learn More
Literature: Carbohydrate Research, , vol. 320, # 3-4 p. 183 - 191

~%

Dextran Structure

Dextran

CAS#:9004-54-0

Learn More
Literature: Carbohydrate Research, , vol. 320, # 3-4 p. 183 - 191

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  2

DownStream  0

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles154

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Dextran-functionalized magnetic fluid mediating magnetohyperthermia for treatment of Ehrlich-solid-tumor-bearing mice: toxicological and histopathological evaluations.

Tumour Biol. 35(4) , 3391-403, (2014)

Dextran-functionalized maghemite fluid (DexMF) has been tested to treat Ehrlich-solid-tumor-bearing mice, evidencing its potential use in mediating magnetohyperthermia in breast cancer treatment. Howe...

Efficacy and safety of antifungal additives in Optisol-GS corneal storage medium.

JAMA Ophthalmol. 132(7) , 832-7, (2014)

Optisol-GS, the most common corneal storage medium in the United States, contains antibacterial but no antifungal supplementation. Most postkeratoplasty endophthalmitis and keratitis cases are now of ...

Antifungal property of hibicuslide C and its membrane-active mechanism in Candida albicans.

Biochimie 95(10) , 1917-22, (2013)

In this study, the antifungal activity and mode of action(s) of hibicuslide C derived from Abutilon theophrasti were investigated. Antifungal susceptibility testing showed that hibicuslide C possessed...

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

(+)-2-propano
MFCD00130935
R(+)-PROPRANOLOL HYDROCHLORIDE &(r)-2-propano
dexpropranolol
Dextran T-40
2r-propranolol
R(+)-PROPRANOLOL HCL
α-D-Glucopyranosyl-(1->6)-α-D-glucopyranosyl-(1->6)-D-glucose
(+)-propranolol
D(+)-propranolol
R-(+)-propranolol
pine pollen
dextropropranolol
Dextran T2000
Dextran
EINECS 232-677-5

 Dextran | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the LogP of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose?
A: LogP of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose is -4.26.
Q: What are the uses of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose?
A: Main uses of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose: Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.
Q: What is the molecular weight of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose?
A: Molecular weight of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose is 504.437.
Q: What is the polar surface area (PSA) of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose?
A: Polar surface area (PSA) of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose is 276.52000.
Q: What is the InChIKey of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose?
A: InChIKey of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose is FZWBNHMXJMCXLU-UHFFFAOYSA-N.
Q: What is the boiling point of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose?
A: Boiling point of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose is 952.8±65.0 °C at 760 mmHg.
Q: What is the safety information for Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose?
A: Safety information for Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose: S24/25.
Q: What is the molecular formula of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose?
A: Molecular formula of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose is C18H32O16.
Q: What English synonyms does Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose have?
A: English synonyms of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose: (+)-2-propano, MFCD00130935, R(+)-PROPRANOLOL HYDROCHLORIDE &(r)-2-propano, dexpropranolol, Dextran T-40, 2r-propranolol, R(+)-PROPRANOLOL HCL, α-D-Glucopyranosyl-(1->6)-α-D-glucopyranosyl-(1->6)-D-glucose, (+)-propranolol, D(+)-propranolol, R-(+)-propranolol, pine pollen, dextropropranolol, Dextran T2000, Dextran, EINECS 232-677-5.
Q: What is the CAS number of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose?
A: CAS number of Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose is 9004-54-0.

 Dextranfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Henan Tianfu Chemical Co., Ltd.
Zhongshan Xingrui Chemical Co. , Ltd.
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