Sugammadex
Sugammadex structure
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Common Name | Sugammadex | ||
|---|---|---|---|---|
| CAS Number | 343306-71-8 | Molecular Weight | 2002.151 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C72H104Na8O48S8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SugammadexSugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Org 25969 |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | Sugammadex (100 mg/kg, IV, once) has a nephroprotective effect when given at the beginning of reperfusion after one hour of ischemic condition on rats[2]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C72H104Na8O48S8 |
| Molecular Weight | 2002.151 |
| Exact Mass | 2000.408813 |
| PSA | 994.80000 |
| LogP | -1.25 |
| Index of Refraction | 1.610 |
| InChIKey | WHRODDIHRRDWEW-VTHZAVIASA-N |
| SMILES | O=C(O)CCSCC1OC2OC3C(CSCCC(=O)O)OC(OC4C(CSCCC(=O)O)OC(OC5C(CSCCC(=O)O)OC(OC6C(CSCCC(=O)O)OC(OC7C(CSCCC(=O)O)OC(OC8C(CSCCC(=O)O)OC(OC9C(CSCCC(=O)O)OC(OC1C(O)C2O)C(O)C9O)C(O)C8O)C(O)C7O)C(O)C6O)C(O)C5O)C(O)C4O)C(O)C3O |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Reversal of 2,27-dioxa-11,18,36,43-tetraza-8,21,33,46-tetrazoniaundecacyclo[46.2.2.23...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL5388777
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3,3',3'',3''',3'''',3''''',3'''''',3'''''''-{[(1S,3S,5S,6S,8S,10S,11S,13S,15S,16S,18S,20S,21S,23S,25S,26S,28S,30S,31S,33S,35S,36S,38S,40S,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56 ;R)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-Hexadecahydroxy-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.2.2.2.2.2.2.2]h exapentacontane-5,10,15,20,25,30,35,40-octay |
| cyclooctakis-(1&;rarr;4)-[6-S-(2-carboxyethyl)-6-thio-α-D-glucopyranosyl] |
| unii-361lpm2t56 |
| Sugammadex |
| UNII361LPM2T56 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the SMILES notation of Org 25969? |
| A: SMILES notation of Org 25969 is O=C(O)CCSCC1OC2OC3C(CSCCC(=O)O)OC(OC4C(CSCCC(=O)O)OC(OC5C(CSCCC(=O)O)OC(OC6C(CSCCC(=O)O)OC(OC7C(CSCCC(=O)O)OC(OC8C(CSCCC(=O)O)OC(OC9C(CSCCC(=O)O)OC(OC1C(O)C2O)C(O)C9O)C(O)C8O)C(O)C7O)C(O)C6O)C(O)C5O)C(O)C4O)C(O)C3O. |
| Q: What is the polar surface area (PSA) of Org 25969? |
| A: Polar surface area (PSA) of Org 25969 is 994.80000. |
| Q: What is the CAS number of Org 25969? |
| A: CAS number of Org 25969 is 343306-71-8. |
| Q: What is the English name of Org 25969? |
| A: The English name of Org 25969 is Org 25969. |
| Q: What is the LogP of Org 25969? |
| A: LogP of Org 25969 is -1.25. |
| Q: What are the uses of Org 25969? |
| A: Main uses of Org 25969: Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury[1][2]. |
| Q: What is the InChIKey of Org 25969? |
| A: InChIKey of Org 25969 is WHRODDIHRRDWEW-VTHZAVIASA-N. |
| Q: What is the molecular formula of Org 25969? |
| A: Molecular formula of Org 25969 is C72H104Na8O48S8. |
| Q: What is the molecular weight of Org 25969? |
| A: Molecular weight of Org 25969 is 2002.151. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Henan Tianfu Chemical Co., Ltd. |