Cytosporone B

Published date: 2022-11-29 15:44:27
Cytosporone B Structure
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Name Cytosporone B CAS# 321661-62-5
Price ￥Inquiry/1g Purity 98.9%
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Period		 1 Day Stock In Stock
 Detail Product Information
Cytosporone B is the first naturally occurring agonist for nuclear orphan receptor Nur77. The molecule binds with high affinity (IC50=0.278 nM) to the ligand-binding domain of Nur77 and stimulates Nur77-dependent activities. Nur77 is also involved in glucose homeostasis, where it induces genes involved in gluconeogenesis. Csn-B physically binds to Nur77 and activates its transactivational activity and translocation to mitochondria to induce apoptosis. It inhibits cancer cell proliferation and tumor growth.
Supplier/Manufacture

ShangHai DC Chemicals Co.,Ltd verified supplier

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