Emavusertib(CA-4948)

Published date: 2022-11-29 15:44:27
Emavusertib(CA-4948) Structure
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Name CA-4948 CAS# 1801344-14-8
Price ￥Inquiry/1g Purity 98.9%
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Period		 1 Day Stock In Stock
 Detail Product Information
CA-4948 is a potent IRAK4/FLT3 inhibtor with anti-tumor activity[1].CA-4948 is over 500-fold more selective for IRAK-4 compared to IRAK-1. CA-4948 reduces TNF-α, IL-1β, IL-6 and IL-8 release from TLR-Stimulated THP-1 Cells with an IC50 <250 nM. CA-4948 also has antiproliferative activity due to inhibition of receptor-type tyrosine-protein kinase FLT3[1].CA-4948 shows anti-tumor activity in animal models including tumors containing MyD88 gene mutations. CA-4948 shows antileukemic activity in mouse models of FLT3 wild-type and FLT3 mutated acute myeloid leukemia (AML)[1].
Supplier/Manufacture

ShangHai DC Chemicals Co.,Ltd verified supplier

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2024-07-15 Emavusertib(CA-4948)
Price: Inquiry
2021-03-17 Emavusertib(CA-4948)
Price: $990.0
2022-05-12 4-Oxazolecarboxamide, N-[5-[(3R)-3-hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-
Price: $Inquiry
2023-12-04 CA4948
Price: ￥Inquiry
2022-09-23 CA-4948
Price: ￥1089.0

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