Azaphen dihydrochloride monohydrate

Modify Date: 2025-08-20 16:59:12

Azaphen dihydrochloride monohydrate structure	Common Name	Azaphen dihydrochloride monohydrate
	CAS Number	63302-99-8	Molecular Weight	388.292
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₂₃Cl₂N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Azaphen dihydrochloride monohydrate

Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin. IC50 Value: Target: SSRIsPipofezine is a tricyclic antidepressant (TCA) approved in Russia for the treatment ofdepression. In addition to its antidepressant action, pipofezine has sedative effects as well, indicating antihistamine activity.

Name	Azaphen dihydrochloride monohydrate
Synonym	More Synonyms

Description	Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin. IC50 Value: Target: SSRIsPipofezine is a tricyclic antidepressant (TCA) approved in Russia for the treatment ofdepression. In addition to its antidepressant action, pipofezine has sedative effects as well, indicating antihistamine activity.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter Research Areas >> Neurological Disease
References	[1]. Shinaev NN, Akzhigitov RG. Azaphen: a return to clinical practice.Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(10):55-6. [2]. Ignatowicz L, Ignatowicz R, Wdowiak MW, Jaremko A. Azaphen in the treatment of enuresis in children.Psychiatr Pol. 1977 Jan-Feb;11(1):29-33. [3]. Liberman SS, Sharova SA. A comparison of the effect of the tricyclic antidepressants azaphen and imizin on the gastrointestinal tracts of experimental animals.Farmakol Toksikol. 1975 Jan-Feb;38(1):29-32. [4]. Misurec J, Náhunek K, Kamenická V, Chmelar M. Proceedings: Influence of azaphen, a new antidepressive drug, on the human EEG. Act Nerv Super (Praha). 1974;16(4):245-6.

Description

Related Catalog

Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter

Research Areas >> Neurological Disease

References

[1]. Shinaev NN, Akzhigitov RG. Azaphen: a return to clinical practice.Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(10):55-6.

[2]. Ignatowicz L, Ignatowicz R, Wdowiak MW, Jaremko A. Azaphen in the treatment of enuresis in children.Psychiatr Pol. 1977 Jan-Feb;11(1):29-33.

[3]. Liberman SS, Sharova SA. A comparison of the effect of the tricyclic antidepressants azaphen and imizin on the gastrointestinal tracts of experimental animals.Farmakol Toksikol. 1975 Jan-Feb;38(1):29-32.

[4]. Misurec J, Náhunek K, Kamenická V, Chmelar M. Proceedings: Influence of azaphen, a new antidepressive drug, on the human EEG. Act Nerv Super (Praha). 1974;16(4):245-6.

Molecular Formula	C₁₆H₂₃Cl₂N₅O₂
Molecular Weight	388.292
Exact Mass	387.122894
InChIKey	VKMOGSQJNTXLNA-UHFFFAOYSA-N
SMILES	CN1CCN(c2cc3c(nn2)Oc2ccccc2N3C)CC1.Cl.Cl.O
Storage condition	2-8℃

Name: qHTS screening for TAG (triacylglycerol) accumulators in algae
Source: 11812
Target: N/A
External Id: FATTTLab-Algae-Lipid

Name: Small-molecule inhibitors of ST2 (IL1RL1)
Source: 20881
Target: interleukin-1 receptor-like 1 isoform [homo sapiens]
External Id: ST2_IL33_Inhibitors_Primary_Screening_77700

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5-Methyl-3-(4-methyl-1-piperazinyl)-5H-pyridazino[3,4-b][1,4]benzoxazine dihydrochloride hydrate

MFCD00220368

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Azaphen (dihydrochloride monohydrate)

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China
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Azaphen dihydrochloride monohydrate

Use of Azaphen dihydrochloride monohydrate

Names

Azaphen dihydrochloride monohydrate Biological Activity

Chemical & Physical Properties

Azaphen dihydrochloride monohydrateBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.