| Name | 9-Hydroxyellipticine hydrochloride | CAS# | 52238-35-4 | |
|---|---|---|---|---|
| Price | ¥Inquiry/1g | Purity | 98.9% | |
| Stocking Period |
1 Day | Stock | In Stock |
| Detail
Product Information
9-hydroxyellipticine, also known as IGIG 929 and LS133324, is a potent cytotoxic and antitumor agent. Structurally, 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine. The hydroxy group in 9-hydroxyellipticines increases the apparent affinity for DNA, stabilisation of toposiomerase II-DNA cleavable complex, oxidation to reactive quinone-imine intermediates, phosphorylation of p53 suppressor proteins and cytotoxicity relative to the parent ellipticines. |