ONO-7579

Published date: 2022-06-22 21:57:40

ONO-7579 Structure
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Name ONO-7579 CAS# 1622212-25-2
Price $Inquiry/100mg $Inquiry/250mg $Inquiry/1g Purity 98.0%
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Period
3 Day Stock 3
Product Webpage: https://www.dcchemicals.com/product_show-ono-7579.html
 Detail Product Information
ONO-7579 (ONO7579) is a novel potent, selective, orally available pan-TRK inhibitor.BDNF significantly increased TRKB phosphorylation in GBC cells and the effects were abrogated by ONO-7579, suppress proliferation in a dose-dependent manner in TYGBK-1 cells.ONO-7579 inhibited BDNF/TRKB-induced migration and invasiveness, particularly in GBC cells harboring wild-type KRAS.ONO-7579 reduced invasiveness of gallbladder cancer (GBC) cells through inhibiting epithelial–mesenchymal transition (EMT) via the extracellular signal-regulated kinase (ERK) or protein kinase B (AKT) pathway.

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DC Chemicals Limited verified supplier

Chemsrc Level: Verified
Product #: 34961
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
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