Mildronate
Mildronate structure
|
Common Name | Mildronate | ||
|---|---|---|---|---|
| CAS Number | 86426-17-7 | Molecular Weight | 182.218 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C6H18N2O4 | Melting Point | N/A | |
| MSDS | Chinese | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of MildronateMildronate dihydrate (Meldonium dihydrate) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Mildronate dihydrate |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Mildronate dihydrate (Meldonium dihydrate) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 34-62 μM (human recombinant BBOX). EC50: 21 μM (human OCTN2). |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C6H18N2O4 |
|---|---|
| Molecular Weight | 182.218 |
| Exact Mass | 182.126663 |
| PSA | 70.62000 |
| Appearance of Characters | white to off-white |
| InChIKey | JFWLFLLRLZSBRA-UHFFFAOYSA-N |
| SMILES | C[N+](C)(C)NCCC(=O)[O-].O.O |
| Storage condition | 2-8°C |
| Water Solubility | H2O: >40mg/mL |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
This table lists relevant public references with title, journal and publication metadata for this compound.
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A rapid method for determination of 22 selected drugs in human urine by UHPLC/MS/MS for clinical application.
J. AOAC Int. 97(6) , 1526-37, (2015) A rapid and sensitive ultra-HPLC/MSIMS (UHPLC/MSIMS) assay method for the simultaneous determination in human urine of 22 drugs belonging to different pharmaceutical groups was developed. The drugs we... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3-(2,2,2-Trimethylhydrazinium)propionate dihydrate |
| Diazanium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, inner salt, hydrate (1:2) |
| Mildronatedehydrate |
| 3-(2,2,2-Trimethyldiazan-2-ium-1-yl)propanoate dihydrate |
| Mildronate |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the physical appearance of Mildronate dihydrate? |
| A: Mildronate dihydrate appears as white to off-white. |
| Q: What is the molecular weight of Mildronate dihydrate? |
| A: Molecular weight of Mildronate dihydrate is 182.218. |
| Q: What are the uses of Mildronate dihydrate? |
| A: Main uses of Mildronate dihydrate: Mildronate dihydrate (Meldonium dihydrate) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes[1]. |
| Q: What is the InChIKey of Mildronate dihydrate? |
| A: InChIKey of Mildronate dihydrate is JFWLFLLRLZSBRA-UHFFFAOYSA-N. |
| Q: What is the safety information for Mildronate dihydrate? |
| A: Safety information for Mildronate dihydrate: 26. |
| Q: What is the SMILES notation of Mildronate dihydrate? |
| A: SMILES notation of Mildronate dihydrate is C[N+](C)(C)NCCC(=O)[O-].O.O. |
| Q: What is the English name of Mildronate dihydrate? |
| A: The English name of Mildronate dihydrate is Mildronate dihydrate. |
| Q: What is the molecular formula of Mildronate dihydrate? |
| A: Molecular formula of Mildronate dihydrate is C6H18N2O4. |
| Q: What English synonyms does Mildronate dihydrate have? |
| A: English synonyms of Mildronate dihydrate: 3-(2,2,2-Trimethylhydrazinium)propionate dihydrate, Diazanium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, inner salt, hydrate (1:2), Mildronatedehydrate, 3-(2,2,2-Trimethyldiazan-2-ium-1-yl)propanoate dihydrate, Mildronate. |
| Q: How is the water solubility of Mildronate dihydrate? |
| A: Water solubility of Mildronate dihydrate: H2O: >40mg/mL. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |