4,6-Dimethoxy-1H-indole

Modify Date: 2025-08-25 10:58:28

4,6-Dimethoxy-1H-indole Structure
4,6-Dimethoxy-1H-indole structure
Common Name 4,6-Dimethoxy-1H-indole
CAS Number 23659-87-2 Molecular Weight 177.200
Density 1.2±0.1 g/cm3 Boiling Point 343.8±22.0 °C at 760 mmHg
Molecular Formula C10H11NO2 Melting Point 122-124ºC
MSDS Chinese USA Flash Point 125.7±12.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4,6-dimethoxy-1H-indole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 343.8±22.0 °C at 760 mmHg
Melting Point 122-124ºC
Molecular Formula C10H11NO2
Molecular Weight 177.200
Flash Point 125.7±12.6 °C
Exact Mass 177.078979
PSA 34.25000
LogP 1.79
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.609
InChIKey NRQBTNARWALYSB-UHFFFAOYSA-N
SMILES COc1cc(OC)c2cc[nH]c2c1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

~23%

4,6-Dimethoxy-1H-indole Structure

4,6-Dimethoxy-1...

CAS#:23659-87-2

Literature: Tetrahedron Letters, , vol. 21, p. 1883 - 1886

~94%

4,6-Dimethoxy-1H-indole Structure

4,6-Dimethoxy-1...

CAS#:23659-87-2

Literature: Hall, Robin J.; Jackson, Anthony H.; Shannon, Patrick V. R.; Oliveira-Campos, Ana M. F. Journal of Chemical Research, Miniprint, 1990 , # 10 p. 2501 - 2519

~47%

4,6-Dimethoxy-1H-indole Structure

4,6-Dimethoxy-1...

CAS#:23659-87-2

Literature: Jumina; Kumar, Naresh; Black, David St.C. Tetrahedron, 2009 , vol. 65, # 12 p. 2591 - 2598

~49%

4,6-Dimethoxy-1H-indole Structure

4,6-Dimethoxy-1...

CAS#:23659-87-2

Literature: Black, David St.C.; Kumar, Naresh; Wong, Laurence C. H. Australian Journal of Chemistry, 1986 , vol. 39, p. 15 - 20

~%

4,6-Dimethoxy-1H-indole Structure

4,6-Dimethoxy-1...

CAS#:23659-87-2

Literature: Tetrahedron Letters, , vol. 21, p. 1883 - 1886

~81%

4,6-Dimethoxy-1H-indole Structure

4,6-Dimethoxy-1...

CAS#:23659-87-2

Literature: Bratulescu, George Tetrahedron Letters, 2008 , vol. 49, # 6 p. 984 - 986

~19%

4,6-Dimethoxy-1H-indole Structure

4,6-Dimethoxy-1...

CAS#:23659-87-2

Literature: Hall, Robin J.; Jackson, Anthony H.; Shannon, Patrick V. R.; Oliveira-Campos, Ana M. F. Journal of Chemical Research, Miniprint, 1990 , # 10 p. 2501 - 2519

~%

4,6-Dimethoxy-1H-indole Structure

4,6-Dimethoxy-1...

CAS#:23659-87-2

Literature: Journal of Chemical Research, Miniprint, , # 10 p. 2501 - 2519

~%

4,6-Dimethoxy-1H-indole Structure

4,6-Dimethoxy-1...

CAS#:23659-87-2

Literature: Journal of Chemical Research, Miniprint, , # 10 p. 2501 - 2519

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 4,6-Dimethoxy-1H-indoleBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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 Synonyms

4,6-Dimethoxy-indol
4,6-Dimethoxy-1H-indole
4,6-dimethoxyindole
1H-Indole,4,6-dimethoxy
MFCD00128213
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