Name | JW 67 | CAS# | 442644-28-2 | |
---|---|---|---|---|
Price | ¥Inquiry/100mg ¥Inquiry/250mg ¥Inquiry/1g | Purity | 98.0% | |
Stocking Period |
1 Day | Stock | 3 | |
Product Webpage: | https://www.dcchemicals.com/product_show-jw67.html |
Detail
Product Information
JW67 inhibits the canonical Wnt signaling with an IC50 of 1.17μM. JW67 affects the multiprotein complex consisting of β-catenin/GSK-3β/AXIN/APC/CK1 that rapidly reduces active β-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth. |