(-)-Bicuculline methochloride

Published date: 2020-12-18 22:54:27
(-)-Bicuculline methochloride Structure
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Name (-)-Bicuculline methochloride CAS# 53552-05-9
Price $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg Purity 98.0%
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Period		 3 Day Stock 3
Product Webpage: https://www.dcchemicals.com/product_show-Bicuculline_methochloride.html
 Detail Product Information
(-)-Bicuculline methochloride is an enantiomer of the GABA antagonist (+)-bicuculline methochloride. It increases the firing rate in rat cortical neurons similar to the (+) isomer but lacks GABA antagonist activity. (-)-Bicuculline methochloride inhibits sodium-independent GABA receptor binding with an IC50 value of 500 μM, which is approximately 100-fold less potent than (+)-bicuculline methochloride, but there is no stereoselectivity for sodium-dependent GABA receptor binding.
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2021-07-26 (4-CYANO-2-NITROPHENYL)BORONICACID
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2021-02-06 (-)-Bicuculline methochloride
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