常用名 | (-)-双甲胆碱 | CAS号 | 53552-05-9 |
---|---|---|---|
价格 | $需询单/100mg $需询单/250mg $需询单/500mg | 纯度 | 98.0% |
备货期 | 3天 | 库存 | 3 |
产品网页 | https://www.dcchemicals.com/product_show-Bicuculline_methochloride.html |
产品详情(用途,包装等)
(-)-Bicuculline methochloride is an enantiomer of the GABA antagonist (+)-bicuculline methochloride. It increases the firing rate in rat cortical neurons similar to the (+) isomer but lacks GABA antagonist activity. (-)-Bicuculline methochloride inhibits sodium-independent GABA receptor binding with an IC50 value of 500 μM, which is approximately 100-fold less potent than (+)-bicuculline methochloride, but there is no stereoselectivity for sodium-dependent GABA receptor binding. |