Clofarabine

Published date: 2020-03-08 16:44:50
Clofarabine Structure
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Name Clofarabine CAS# 123318-82-1
Price $250.0/100mg $500.0/250mg $1000.0/1g Purity 98.0%
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Period		 3 Day Stock In Stock
Product Webpage: https://www.dcchemicals.com/product_show-Clofarabine.html
 Detail Product Information
Clofarabine(Clolar; Clofarex) inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase. IC50 Value: 65 nM Target: in vitro: Clofarabine is a second generation purine nucleoside analog with antineoplastic activity. It is phosphorylated intracellularly, which inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase, resulting in inhibition of DNA repair and synthesis of DNA and RNA. This nucleoside analog also disrupts mitochondrial function and membrane integrity, resulting in the release of pre-apoptotic factors, including cytochrome C and apoptotic-inducing factor, which activate apoptosis. in vivo: Clofarabine is used for treating relapsed or refractory acute lymphoblastic leukaemia (ALL) in children, after at least two other types of treatment have failed.
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DC Chemicals Limited verified supplier

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Contact Phone #: 13564518121
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Clofarabine price is $250.0/100mg. Find complete details about Clofarabine product information includes price/quote, purity, stocking period etc. from DC Chemicals Limited>>Mobile(AMP) version: Clofarabine Price from Supplier Brand DC Chemicals Limited

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