glucosylmannitol

Modify Date: 2026-07-07 18:52:33

glucosylmannitol Structure
glucosylmannitol structure
Common Name glucosylmannitol
CAS Number 64519-82-0 Molecular Weight 344.312
Density 1.7±0.1 g/cm3 Boiling Point 788.5±60.0 °C at 760 mmHg
Molecular Formula C12H24O11 Melting Point 215-217°C
MSDS Chinese USA Flash Point 430.7±32.9 °C

 Use of glucosylmannitol


Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name Isomalt
Synonym More Synonyms

 glucosylmannitol Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].
Related Catalog
In Vivo The chronic toxicity of orally administered isomalt as a part of diet has been studied in animals and it was found to be a safe substance. It did not affect the mortality rate of the animals, and there was no evidence of carcinogenicity, or adverse effects on fertility, reproductive performance or development[1].
References

[1]. Tuderman AK, et al. Isomalt and its diastereomer mixtures as stabilizing excipients with freeze-dried lactate dehydrogenase. Int J Pharm. 2018 Mar 1;538(1-2):287-295.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.7±0.1 g/cm3
Boiling Point 788.5±60.0 °C at 760 mmHg
Melting Point 215-217°C
Molecular Formula C12H24O11
Molecular Weight 344.312
Flash Point 430.7±32.9 °C
Exact Mass 344.131866
PSA 401.06000
LogP -5.72
Vapour Pressure 0.0±6.2 mmHg at 25°C
Index of Refraction 1.634
InChIKey SERLAGPUMNYUCK-BLEZHGCXSA-N
SMILES OCC(O)C(O)C(O)C(O)COC1OC(CO)C(O)C(O)C1O
Storage condition 2-8°C

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ4394500
CHEMICAL NAME :
D-Glucitol, 6-O-alpha-D-glucopyranosyl-, mixed with 1-O-alpha-D-glucopyranosyl-D-mannitol
CAS REGISTRY NUMBER :
64519-82-0
LAST UPDATED :
199312
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H24-O11.C12-H24-O11
MOLECULAR WEIGHT :
688.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
125 mg/kg
SEX/DURATION :
female 5 day(s) pre-mating female 1-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 27,631,1989

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xn
Risk Phrases R20/21/22
Safety Phrases 22-26-36/37/39-45
RIDADR NONH for all modes of transport
RTECS LZ4394500
HS Code 2940000000

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2940000000

 Articles25

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Assessment of isomalt for colon-specific delivery and its comparison with lactulose.

AAPS PharmSciTech 14(1) , 53-9, (2013)

Lactulose is used as a triggering substance in a unique colon-specific delivery technology called CODESTM. Colonic microflora degrades lactulose and forms short-chain fatty acids to activate the CODES...

Effect of isomalt consumption on faecal microflora and colonic metabolism in healthy volunteers.

Br. J. Nutr. 95(1) , 40-50, (2006)

Due to its low digestibility in the small intestine, a major fraction of the polyol isomalt reaches the colon. However, little is known about effects on the intestinal microflora. During two 4-week pe...

Effects of isomalt consumption on gastrointestinal and metabolic parameters in healthy volunteers.

Br. J. Nutr. 94(4) , 575-81, (2005)

The polyol isomalt (Palatinit) is a well established sugar replacer. The impact of regular isomalt consumption on metabolism and parameters of gut function in nineteen healthy volunteers was examined ...

 glucosylmannitolBioassay

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This table contains target information, in‑vitro & in‑vivo assay data for this compound.

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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1-O-α-D-Glucopyranosyl-D-mannitol
Plaltinitol
PALATINOL
ISOMALT USP
MFCD00190708
PALATINIT
hydrogenated isomaltulose
glucosylmannitol
Isomaltitol
EINECS 203-252-1
1-O-a-D-glucopyranosyl-D-mannitol
PALATINITOL

 glucosylmannitol | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of Isomalt?
A: Polar surface area (PSA) of Isomalt is 401.06000.
Q: What is the molecular formula of Isomalt?
A: Molecular formula of Isomalt is C12H24O11.
Q: What English synonyms does Isomalt have?
A: English synonyms of Isomalt: 1-O-α-D-Glucopyranosyl-D-mannitol, Plaltinitol, PALATINOL, ISOMALT USP, MFCD00190708, PALATINIT, hydrogenated isomaltulose, glucosylmannitol, Isomaltitol, EINECS 203-252-1, 1-O-a-D-glucopyranosyl-D-mannitol, PALATINITOL.
Q: What is the CAS number of Isomalt?
A: CAS number of Isomalt is 64519-82-0.
Q: What is the InChIKey of Isomalt?
A: InChIKey of Isomalt is SERLAGPUMNYUCK-BLEZHGCXSA-N.
Q: What are the storage conditions for Isomalt?
A: Storage conditions for Isomalt: 2-8°C.
Q: What are the uses of Isomalt?
A: Main uses of Isomalt: Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].
Q: What is the melting point of Isomalt?
A: Melting point of Isomalt is 215-217°C.
Q: What is the English name of Isomalt?
A: The English name of Isomalt is Isomalt.
Q: What is the molecular weight of Isomalt?
A: Molecular weight of Isomalt is 344.312.

 glucosylmannitolfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
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