Falcarinol
Falcarinol structure
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Common Name | Falcarinol | ||
|---|---|---|---|---|
| CAS Number | 21852-80-2 | Molecular Weight | 244.372 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 370.6±42.0 °C at 760 mmHg | |
| Molecular Formula | C17H24O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 163.4±20.9 °C | |
Use of FalcarinolFalcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1,9-Heptadecadiene-4,6-diyn-3-ol |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Panaxynol inhibits the sphere-forming ability of NSCLC CSCs by inducing apoptosis. Panaxynol suppresses the viability of NSCLC cells with no effects on normal cells[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 370.6±42.0 °C at 760 mmHg |
| Molecular Formula | C17H24O |
| Molecular Weight | 244.372 |
| Flash Point | 163.4±20.9 °C |
| Exact Mass | 244.182709 |
| PSA | 20.23000 |
| LogP | 6.96 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.507 |
| InChIKey | UGJAEDFOKNAMQD-QXPKXGMISA-N |
| SMILES | C=CC(O)C#CC#CCC=CCCCCCCC |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2905290000 |
|---|
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~69%
Falcarinol CAS#:21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
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~40%
Falcarinol CAS#:21852-80-2 |
| Literature: McLaughlin, Noel P.; Butler, Eibhlin; Evans, Paul; Brunton, Nigel P.; Koidis, Anastasios; Rai, Dilip K. Tetrahedron, 2010 , vol. 66, # 51 p. 9681 - 9687 |
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~%
Falcarinol CAS#:21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
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~%
Falcarinol CAS#:21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~%
Falcarinol CAS#:21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~%
Falcarinol CAS#:21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~%
Falcarinol CAS#:21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~%
Falcarinol CAS#:21852-80-2 |
| Literature: Zheng, Guangrong; Lu, Wei; Aisa, Haji A.; Cai, Junchao Tetrahedron Letters, 1999 , vol. 40, # 11 p. 2181 - 2182 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
|---|---|
| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2905290000 |
|---|---|
| Summary | 2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Carotatoxin |
| (-)-Falcarinol |
| (-)-Carotatoxin |
| (-)-Panaxynol |
| (−)-(3R)-falcarinol |
| (3R,9Z)-1,9-Heptadecadiene-4,6-diyn-3-ol |
| Falcarinol |
| Panaxynol |
| (3R,9Z)-Heptadeca-1,9-diene-4,6-diyn-3-ol |
| Falcarinol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of 1,9-Heptadecadiene-4,6-diyn-3-ol? |
| A: LogP of 1,9-Heptadecadiene-4,6-diyn-3-ol is 6.96. |
| Q: What is the boiling point of 1,9-Heptadecadiene-4,6-diyn-3-ol? |
| A: Boiling point of 1,9-Heptadecadiene-4,6-diyn-3-ol is 370.6±42.0 °C at 760 mmHg. |
| Q: What is the molecular formula of 1,9-Heptadecadiene-4,6-diyn-3-ol? |
| A: Molecular formula of 1,9-Heptadecadiene-4,6-diyn-3-ol is C17H24O. |
| Q: What English synonyms does 1,9-Heptadecadiene-4,6-diyn-3-ol have? |
| A: English synonyms of 1,9-Heptadecadiene-4,6-diyn-3-ol: Carotatoxin, (-)-Falcarinol, (-)-Carotatoxin, (-)-Panaxynol, (−)-(3R)-falcarinol, (3R,9Z)-1,9-Heptadecadiene-4,6-diyn-3-ol, Falcarinol, Panaxynol, (3R,9Z)-Heptadeca-1,9-diene-4,6-diyn-3-ol, Falcarinol. |
| Q: What are the uses of 1,9-Heptadecadiene-4,6-diyn-3-ol? |
| A: Main uses of 1,9-Heptadecadiene-4,6-diyn-3-ol: Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1]. |
| Q: What is the polar surface area (PSA) of 1,9-Heptadecadiene-4,6-diyn-3-ol? |
| A: Polar surface area (PSA) of 1,9-Heptadecadiene-4,6-diyn-3-ol is 20.23000. |
| Q: What are the upstream materials of 1,9-Heptadecadiene-4,6-diyn-3-ol? |
| A: Related upstream materials(CAS) of 1,9-Heptadecadiene-4,6-diyn-3-ol: 135457-18-0;4117-14-0;14304-31-5;445494-03-1;224636-36-6. |
| Q: What is the CAS number of 1,9-Heptadecadiene-4,6-diyn-3-ol? |
| A: CAS number of 1,9-Heptadecadiene-4,6-diyn-3-ol is 21852-80-2. |
| Q: What is the InChIKey of 1,9-Heptadecadiene-4,6-diyn-3-ol? |
| A: InChIKey of 1,9-Heptadecadiene-4,6-diyn-3-ol is UGJAEDFOKNAMQD-QXPKXGMISA-N. |
| Q: What is the SMILES notation of 1,9-Heptadecadiene-4,6-diyn-3-ol? |
| A: SMILES notation of 1,9-Heptadecadiene-4,6-diyn-3-ol is C=CC(O)C#CC#CCC=CCCCCCCC. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |