cis-4-Hydroxyproline
cis-4-Hydroxyproline structure
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Common Name | cis-4-Hydroxyproline | ||
|---|---|---|---|---|
| CAS Number | 2584-71-6 | Molecular Weight | 131.130 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 355.2±42.0 °C at 760 mmHg | |
| Molecular Formula | C5H9NO3 | Melting Point | 243 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 168.6±27.9 °C | |
Summary: cis-4-hydroxy-D-proline (Chinese name: 顺式-4-羟基-D-脯氨酸, CAS number: 2584-71-6) is a white crystalline powder with a molecular formula of C5H9NO3 and a molecular weight of 131.130. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | cis-4-hydroxy-D-proline |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 355.2±42.0 °C at 760 mmHg |
| Melting Point | 243 °C (dec.)(lit.) |
| Molecular Formula | C5H9NO3 |
| Molecular Weight | 131.130 |
| Flash Point | 168.6±27.9 °C |
| Exact Mass | 131.058243 |
| PSA | 69.56000 |
| LogP | -1.84 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.540 |
| InChIKey | PMMYEEVYMWASQN-QWWZWVQMSA-N |
| SMILES | O=C(O)C1CC(O)CN1 |
| Water Solubility | 5 g/100 mL |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S24/25-S22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933990090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 10 | |
CAS#:51-35-4
CAS#:176966-56-6
CAS#:135042-12-5
CAS#:502442-57-1
CAS#:108782-06-5
CAS#:232262-82-7
CAS#:77450-00-1
CAS#:232262-93-0
CAS#:141850-54-6
CAS#:130930-25-5
CAS#:132666-67-2
CAS#:114676-59-4
CAS#:114676-47-0
CAS#:114676-97-0![[(2R,4R)-4-(2,6-diaminopurin-9-yl)pyrrolidin-2-yl]methanol structure](https://image.chemsrc.com/caspic/461/135042-30-7.png)
CAS#:135042-30-7
CAS#:1499-56-5
CAS#:147226-04-8This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Use of Commercial Dry Yeast Products Rich in Mannoproteins for White and Rosé Sparkling Wine Elaboration.
J. Agric. Food Chem. 63 , 5670-81, (2015) In sparkling wines, mannoproteins released during yeast autolysis largely affect their final quality. This process is very slow and may take several months. The aim of this work was to study the effec... |
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Direct high-performance liquid chromatographic enantioseparation of secondary amino acids on Cinchona alkaloid-based chiral zwitterionic stationary phases. Unusual temperature behavior.
J. Chromatogr. A. 1363 , 169-77, (2014) Two chiral stationary phases containing a quinine- or a quinidine-based zwitterionic ion-exchanger as chiral selector were applied for the enantioseparation of 27 unusual cyclic secondary α-amino acid... |
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Biological, biochemical and biomechanical characterisation of articular cartilage from the porcine, bovine and ovine hip and knee.
Biomed Mater Eng 25 , 381-95, (2015) This study aimed to determine the optimal starting material for the development of an acellular osteochondral graft. Osteochondral tissues from three different species were characterised; pig (6 month... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 ...
Source: ChEMBL
Target: Proton-coupled amino acid transporter 1
External Id: CHEMBL1919336
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (2R,4R)-(+)-4-Hydroxy-2-pyrrolidinecarboxylic acid D-allo-Hydroxyproline |
| H-D-cis-Hyp-OH |
| (2R,4R)-4-Hydroxypyrrolidine-2-carboxylic Acid |
| (4R)-4-Hydroxy-D-proline |
| cis-4-Hydroxyproline |
| D-cis-Hydroxyproline |
| (2R,4R)-(+)-4-Hydroxy-2-pyrrolidinecarboxylic acid |
| d-cis-4-hydroxyproline |
| cis-4-Hydroxy-D-proline |
| EINECS 219-963-5 |
| MFCD00005252 |
| D-allo-Hydroxyproline |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of cis-4-hydroxy-D-proline? |
| A: Polar surface area (PSA) of cis-4-hydroxy-D-proline is 69.56000. |
| Q: What is the SMILES notation of cis-4-hydroxy-D-proline? |
| A: SMILES notation of cis-4-hydroxy-D-proline is O=C(O)C1CC(O)CN1. |
| Q: What is the safety information for cis-4-hydroxy-D-proline? |
| A: Safety information for cis-4-hydroxy-D-proline: S24/25-S22. |
| Q: What is the boiling point of cis-4-hydroxy-D-proline? |
| A: Boiling point of cis-4-hydroxy-D-proline is 355.2±42.0 °C at 760 mmHg. |
| Q: What is the melting point of cis-4-hydroxy-D-proline? |
| A: Melting point of cis-4-hydroxy-D-proline is 243 °C (dec.)(lit.). |
| Q: What is the LogP of cis-4-hydroxy-D-proline? |
| A: LogP of cis-4-hydroxy-D-proline is -1.84. |
| Q: What is the CAS number of cis-4-hydroxy-D-proline? |
| A: CAS number of cis-4-hydroxy-D-proline is 2584-71-6. |
| Q: What is the molecular formula of cis-4-hydroxy-D-proline? |
| A: Molecular formula of cis-4-hydroxy-D-proline is C5H9NO3. |
| Q: What are the upstream materials of cis-4-hydroxy-D-proline? |
| A: Related upstream materials(CAS) of cis-4-hydroxy-D-proline: 51-35-4;176966-56-6;135042-12-5;502442-57-1;108782-06-5;232262-82-7;77450-00-1;232262-93-0. |
| Q: What English synonyms does cis-4-hydroxy-D-proline have? |
| A: English synonyms of cis-4-hydroxy-D-proline: (2R,4R)-(+)-4-Hydroxy-2-pyrrolidinecarboxylic acid D-allo-Hydroxyproline, H-D-cis-Hyp-OH, (2R,4R)-4-Hydroxypyrrolidine-2-carboxylic Acid, (4R)-4-Hydroxy-D-proline, cis-4-Hydroxyproline, D-cis-Hydroxyproline, (2R,4R)-(+)-4-Hydroxy-2-pyrrolidinecarboxylic acid, d-cis-4-hydroxyproline, cis-4-Hydroxy-D-proline, EINECS 219-963-5, MFCD00005252, D-allo-Hydroxyproline. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |