Stereoselectivity in the reduction of aliphatic. alpha.-ketols with aluminum hydride reagents

JA Katzenellenbogen, SB Bowlus

Index: Katzenellenbogen,J.A.; Bowlus,S.B. Journal of Organic Chemistry, 1973 , vol. 38, p. 627 - 632

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Citation Number: 50

Abstract

Results Synthesis of a-Ketols.---The a-ketols utilized in this study xere prepared either by the mercuric ion catalyzed hydration of propargylic alcohols4c or by addition of 2-lithio-2-methyl- l, 3-djthiane to carbonyl compounds, followed by mercuric ion assisted hydrolysis of the dithioketa14"(Scheme I). Yields, physical con-

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