Tetrahedron Letters

Nafion®-catalyzed microwave-assisted Ritter reaction: an atom-economic solvent-free synthesis of amides

V Polshettiwar, RS Varma

Index: Polshettiwar, Vivek; Varma, Rajender S. Tetrahedron Letters, 2008 , vol. 49, # 16 p. 2661 - 2664

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Citation Number: 67

Abstract

Amides are common moieties in naturally occurring substances like peptides and proteins and are also found in various synthetic materials. 1 and 2 This makes the amide functionality an important building block in synthetic chemistry and many methods for its synthesis were reported in the literature. 1 In general, amides are formed by the condensation of carboxylic acid and amines, using various coupling agents. 3 Although good results were obtained using this ...