Nucleic Acids Symposium Series 2008-01-01

Hydrolysis of single linkage in long DNA using oligonucleotide-multiphosphonate conjugates and Ce IV/EDTA.

Yuta Suzuki, Tuomas Lönnberg, Makoto Komiyama

Index: Nucleic Acids Symp. Ser. (52) , 379-80, (2008)

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Abstract

Only one phosphodiester linkage in long DNA was hydrolyzed simply by using two components: oligonucleotide-multiphosphonate conjugates ("gapmers") and Ce(IV)/EDTA (Fig. 1).