e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Solvent attack in Grignard reagent formation from bromocyclopropane and 1-bromohexane in diethyl ether
…, F Ungvary, R Batlaw, KE Lawrence
Index: Garst, John F.; Ungvary, Ferenc; Batlaw, Rajnish; Lawrence, Kathryn Easton Journal of the American Chemical Society, 1991 , vol. 113, # 14 p. 5392 - 5397
Abstract: In the reaction of magnesium with bromocyclopropane in diethyl ether at reflux, intermediate cyclopropyl radicals attack the solvent, giving cyclopropane (20-30 mol/100 mol of bromocyclopropane consumed) and solvent-derived products. In contrast, the similar reaction of 1-bromohexane gives no more than 0.5 mol of hexane from solvent attack by hexyl radicals. These data are consistent with calculations based on a mechanism (D ...