Silica sulfuric acid as a reusable catalyst for the conversion of ketones into amides by a Schmidt reaction under solvent-free conditions

…, A Hassankhani, E Mosaddegh

Index: Eshghi, Hossein; Hassankhani, Asadollah; Mosaddegh, Elaheh Journal of Chemical Research, 2006 , # 4 p. 218 - 219

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Citation Number: 3

Abstract

Silica sulfuric acid is a highly efficient reagent for the conversion of a variety of ketones into the corresponding amides by a Schmidt reaction under solvent-free conditions. Cyclic, aliphatic and aromatic ketones with electron-donating or withdrawing substituents may be converted easily in excellent yield. The major advantages of this method are: operational simplicity, the ready availability of the reagent, selectivity, general applicability, mild ...