Organic & Biomolecular Chemistry 2012-02-14

Direct amination of α-substituted nitroacetates using di-tert-butyl azodicarboxylate catalyzed by Hatakeyama's catalyst β-ICD.

Cong-Bin Ji, Yun-Lin Liu, Xiao-Li Zhao, Yin-Long Guo, Hao-Yang Wang, Jian Zhou

Index: Org. Biomol. Chem. 10(6) , 1158-61, (2012)

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Abstract

We report the first example of catalytic asymmetric direct amination of α-monosubstituted nitroacetates using di-tert-butyl azodicarboxylate. The simple and easily available Hatakeyama's catalyst β-ICD 11 was found to be a highly enantioselective catalyst for this reaction.

Structure	Name/CAS No.	Molecular Formula	Articles
	Di-tert-Butyl azodicarboxylate CAS:870-50-8	C₁₀H₁₈N₂O₄

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[J. Am. Chem. Soc. 128 , 16044, (2006)]

Chirally aminated 2-naphthols--organocatalytic synthesis of ...
2006-02-06
[Angew. Chem. Int. Ed. Engl. 45(7) , 1147-1151, (2006)]

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2015-07-06
[Angew. Chem. Int. Ed. Engl. 54(28) , 8198-202, (2015)]

M. Kiankarimi et al.
[Tetrahedron Lett. 40 , 4497 , (1999)]

J.L. Vicario et al.
[Tetrahedron Lett. 40 , 7123 , (1999)]

Direct amination of α-substituted nitroacetates using di-tert-butyl azodicarboxylate catalyzed by Hatakeyama's catalyst β-ICD.

Abstract

Related Compounds