Il Farmaco; edizione scientifica 1980-05-01

(+/-)-1-(Adamantan-2-yl)-2-propanamine and other amines derived from 2-adamantanone.

E Mariani, P Schenone, F Bondavalli, E Lampa, E Marmo

Index: Farmaco. Sci. 35(5) , 430-40, (1980)

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Abstract

The synthesis of (+/-)-1-(adamantan-2-yl)-2-propanamine (VI), its N,N-dimethyl derivative (VII) and other amines (VIII), (IX) and (X), starting from 2-adamantanone, is described. Some of these amines showed antiparkinson activity in mice.