Neurochemistry International 2011-01-01

The lumped constant of α-methyl-l-tryptophan is not influenced by drugs acting through serotonergic system

Nela Pivac, Mirko Diksic, Nela Pivac, Mirko Diksic, Nela Pivac, Mirko Diksic

Index: Neurochem. Int. 58(7) , 826-32, (2011)

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Abstract

Highlights ► Lumped constant converts brain trapping of tracer α-[ 14C]MTrp into 5-HT synthesis. ► The effects of drugs on the lumped constant (LC) stability were investigated. ► The regional values of LC in each of these three sets were normally distributed. ► LC values calculated as the mean did not differ significantly between experiments.