Organic letters

An Unexpected Oxidation of Unactivated Methylene C–H Using DIB/TBHP Protocol

Y Zhao, WL Yim, CK Tan, YY Yeung

Index: Zhao, Yi; Yim, Wai-Leung; Tan, Chong Kiat; Yeung, Ying-Yeung Organic Letters, 2011 , vol. 13, # 16 p. 4308 - 4311

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Citation Number: 39

Abstract

An in situ generated hypervalent iodine species, bis (tert-butylperoxy) iodobenzene, was used as a peroxy radical source for the oxidation of unreactive, remote, and isolated alkyl (cyclic or aliphatic) esters and amides to the corresponding keto compounds under very mild conditions.